CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030065
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 N-acetylneuraminic acid synthase 
Protein Synonyms/Alias
 N-acetylneuraminic acid synthase (Sialic acid synthase) (Predicted), isoform CRA_a; Protein Nans 
Gene Name
 Nans 
Gene Synonyms/Alias
 Nans_predicted; rCG_55111 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
61QKSELEFKFNRKALEacetylation[1]
74LERPYTSKHSWGKTYacetylation[1]
79TSKHSWGKTYGEHKRacetylation[1]
85GKTYGEHKRHLEFSHacetylation[1]
145NNFPYLEKTAKKGRPacetylation[1]
243ERHITLDKTWKGSDHacetylation[1]
333DIFNLVGKKVLVTIEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 359 AA 
Protein Sequence
MPLELELCPG RWVGGQHPCF IIAEIGQNHQ GDLDVAKRMI RTAKECGADC AKFQKSELEF 60
KFNRKALERP YTSKHSWGKT YGEHKRHLEF SHDQYKELQS YAQEIGIFFT ASGMDEMAVE 120
FLHELNVPFF KVGSGDTNNF PYLEKTAKKG RPMVISSGMQ SMDTMKQVYQ IVKPLNPNFC 180
FLQCTSAYPL QPEDANLRVI SEYQKLFPDI PIGYSGHETG IAISVAAVAL GAKVLERHIT 240
LDKTWKGSDH LASLEPGELA ELVRSVRLVE RALGSPAKQL LPCEMACNEK LGKSVVAKVK 300
IPAGTILTLD MLTVKVGEPK GYPPEDIFNL VGKKVLVTIE EDDTVMEESV ESQSKKIKA 359 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0047444; F:N-acylneuraminate-9-phosphate synthase activity; IEA:Compara.
 GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro. 
Interpro
 IPR006190; AFP_Neu5c_C.
 IPR013785; Aldolase_TIM.
 IPR013132; Neu5Ac_N.
 IPR013974; SAF. 
Pfam
 PF03102; NeuB
 PF08666; SAF 
SMART
 SM00858; SAF 
PROSITE
 PS50844; AFP_LIKE 
PRINTS