| Tag | Content |
|---|
| CPLM ID | CPLM-002241 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation factor 1-alpha 2 |
Protein Synonyms/Alias | EF-1-alpha-2 |
Gene Name | Ef1alpha100E |
Gene Synonyms/Alias | EF1a; F2; CG1873 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 30 | TTGHLIYKCGGIDKR | acetylation | [1] | | 41 | IDKRTIEKFEKEAQE | acetylation | [1] | | 44 | RTIEKFEKEAQEMGK | acetylation | [1] | | 55 | EMGKGSFKYAWVLDK | acetylation | [1] | | 172 | ARYEEIKKEVSSYIK | acetylation | [1] | | 255 | LPLQDVYKIGGIGTV | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. |
Sequence Annotation | NP_BIND 14 21 GTP (By similarity).
NP_BIND 91 95 GTP (By similarity).
NP_BIND 153 156 GTP (By similarity).
MOD_RES 301 301 5-glutamyl glycerylphosphorylethanolamine
MOD_RES 374 374 5-glutamyl glycerylphosphorylethanolamine |
Keyword | Complete proteome; Cytoplasm; Elongation factor; GTP-binding; Nucleotide-binding; Phosphoprotein; Protein biosynthesis; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 462 AA |
Protein Sequence | MGKEKIHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAQEMG KGSFKYAWVL 60
DKLKAERERG ITIDIALWKF ETSKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGT 120
GEFEAGISKN GQTREHALLA FTLGVKQLIV GVNKMDSTEP PYSEARYEEI KKEVSSYIKK 180
IGYNPASVAF VPISGWHGDN MLEPSEKMPW FKGWSVERKE GKAEGKCLID ALDAILPPQR 240
PTDKPLRLPL QDVYKIGGIG TVPVGRVETG LLKPGMVVNF APVNLVTEVK SVEMHHEALT 300
EAMPGDNVGF NVKNVSVKEL RRGYVAGDSK NNPPRGAADF TAQVIVLNHP GQIANGYTPV 360
LDCHTAHIAC KFSEIKEKCD RRTGKTTETE PKAIKSGDAA IIVLVPSKPL CVESFQEFPP 420
LGRFAVRDMR QTVAVGVIKS VNFKETTSGK VTKAAEKAQK KK 462 |
Gene Ontology | GO:0005853; C:eukaryotic translation elongation factor 1 complex; ISS:FlyBase. GO:0005811; C:lipid particle; IDA:FlyBase. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0003746; F:translation elongation factor activity; ISS:FlyBase. GO:0006184; P:GTP catabolic process; IEA:GOC. GO:0022008; P:neurogenesis; IMP:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |