CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031528
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear pore complex protein Nup50 
Protein Synonyms/Alias
 cDNA FLJ54237, highly similar to Nucleoporin 50 kDa 
Gene Name
 NUP50 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
8MEVASEKKTDPSSLGubiquitination[1]
25SASFNFGKKVDSSVLubiquitination[2, 3]
96EENDEPPKVVVTEVKubiquitination[4]
103KVVVTEVKEEDAFYSubiquitination[4]
210EDADELHKILLEKKDubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 218 AA 
Protein Sequence
MEVASEKKTD PSSLGATSAS FNFGKKVDSS VLGSLSSVPL TGFSFSPGNS SLFGKDTTQS 60
KPVSSPFPTK PLEGQAEGDS GECKGGDEEE NDEPPKVVVT EVKEEDAFYS KKCKLFYKKD 120
NEFKEKGIGT LHLKPTANQK TQLLVRADTN LGNILLNVLI PPNMPCTRTG KNNVLIVCVP 180
NPPIDEKNAT MPVTMLIRVK TSEDADELHK ILLEKKDA 218 
Gene Ontology
 GO:0046907; P:intracellular transport; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR000156; Ran_bind_dom. 
Pfam
 PF00638; Ran_BP1 
SMART
 SM00160; RanBD 
PROSITE
 PS50196; RANBD1 
PRINTS