| Tag | Content |
|---|
| CPLM ID | CPLM-010973 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquitin-like-specific protease 1 |
Protein Synonyms/Alias | |
Gene Name | ULP1 |
Gene Synonyms/Alias | YPL020C; LPB11C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 157 | SSDTRKHKFDTSTWA | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SMT3 to its mature form and deconjugation of SMT3 from targeted proteins. Has an essential role in the G2/M phase of the cell cycle. |
Sequence Annotation | REGION 432 621 Protease.
ACT_SITE 514 514
ACT_SITE 531 531
ACT_SITE 580 580
MOD_RES 21 21 Phosphoserine.
MOD_RES 25 25 Phosphoserine.
MOD_RES 179 179 Phosphothreonine.
MOD_RES 264 264 Phosphoserine. |
Keyword | 3D-structure; Complete proteome; Hydrolase; Phosphoprotein; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 621 AA |
Protein Sequence | MSVEVDKHRN TLQYHKKNPY SPLFSPISTY RCYPRVLNNP SESRRSASFS GIYKKRTNTS 60
RFNYLNDRRV LSMEESMKDG SDRASKAGFI GGIRETLWNS GKYLWHTFVK NEPRNFDGSE 120
VEASGNSDVE SRSSGSRSSD VPYGLRENYS SDTRKHKFDT STWALPNKRR RIESEGVGTP 180
STSPISSLAS QKSNCDSDNS ITFSRDPFGW NKWKTSAIGS NSENNTSDQK NSYDRRQYGT 240
AFIRKKKVAK QNINNTKLVS RAQSEEVTYL RQIFNGEYKV PKILKEERER QLKLMDMDKE 300
KDTGLKKSII DLTEKIKTIL IENNKNRLQT RNENDDDLVF VKEKKISSLE RKHKDYLNQK 360
LKFDRSILEF EKDFKRYNEI LNERKKIQED LKKKKEQLAK KKLVPELNEK DDDQVQKALA 420
SRENTQLMNR DNIEITVRDF KTLAPRRWLN DTIIEFFMKY IEKSTPNTVA FNSFFYTNLS 480
ERGYQGVRRW MKRKKTQIDK LDKIFTPINL NQSHWALGII DLKKKTIGYV DSLSNGPNAM 540
SFAILTDLQK YVMEESKHTI GEDFDLIHLD CPQQPNGYDC GIYVCMNTLY GSADAPLDFD 600
YKDAIRMRRF IAHLILTDAL K 621 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |