UniProt Accession

 E9QNH7_MOUSE; E9QNH7 

Genbank Protein ID

 AL845257 

Genbank Nucleotide ID

  

Protein Name

 Acyl-CoA-binding domain-containing protein 5 

Protein Synonyms/Alias

  

Gene Name

 Acbd5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
53	TRFEAAVKVIQSLPK	ubiquitination	[1]
60	KVIQSLPKNGSFQPT	ubiquitination	[1]
79	LKFYSFYKQATEGPC	ubiquitination	[1]
158	VEDKKSSKSSDLTSD	ubiquitination	[1]
176	VLTSSNAKAVNGKAE	ubiquitination	[1]
257	TRSSEDEKPGDESSQ	ubiquitination	[1]
447	NVLQRLHKLETLTAS	acetylation	[2, 3]
447	NVLQRLHKLETLTAS	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 509 AA 

Protein Sequence

Gene Ontology

 GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara.
 GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro. 

Interpro

 IPR022408; Acyl-CoA-binding_prot_CS.
 IPR000582; Acyl-CoA-binding_protein.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR016347; M-assoc_diazepam-bd-inh. 

Pfam

 PF00887; ACBP 

SMART

  

PROSITE

 PS00880; ACB_1
 PS51228; ACB_2 

PRINTS

 PR00689; ACOABINDINGP.