CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001506
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SOGA1 
Protein Synonyms/Alias
 SOGA family member 1; Suppressor of glucose by autophagy; Suppressor of glucose, autophagy-associated protein 1; N-terminal form; C-terminal 80 kDa form; 80-kDa SOGA fragment 
Gene Name
 SOGA1 
Gene Synonyms/Alias
 C20orf117; KIAA0889; SOGA 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
798QMELKTGKGAGERAGubiquitination[1]
809ERAGPDWKAALQRERubiquitination[2]
867QQVEQQVKELQNRLSubiquitination[2]
878NRLSQLQKAADPWVLubiquitination[1, 2]
886AADPWVLKHSELEKQubiquitination[2]
1009RSYTAPDKTGIRVYYubiquitination[1]
1048GFLFTTAKPKESAEAubiquitination[1]
1286RAKPEPPKYGIVQEFubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
 Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity). 
Sequence Annotation
 MOD_RES 931 931 Phosphoserine.
 MOD_RES 1017 1017 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Phosphoprotein; Polymorphism; Reference proteome; Secreted. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1423 AA 
Protein Sequence
MLEMRDVYME EDVYQLQELR QQLDQASKTC RILQYRLRKA ERRSLRAAQT GQVDGELIRG 60
LEQDVKVSKD ISMRLHKELE VVEKKRARLE EENEELRQRL IETELAKQVL QTELERPREH 120
SLKKRGTRSL GKADKKTLVQ EDSADLKCQL HFAKEESALM CKKLTKLAKE NDSMKEELLK 180
YRSLYGDLDS ALSAEELADA PHSRETELKV HLKLVEEEAN LLSRRIVELE VENRGLRAEM 240
DDMKDHGGGC GGPEARLAFS ALGGGECGES LAELRRHLQF VEEEAELLRR SSAELEDQNK 300
LLLNELAKFR SEHELDVALS EDSCSVLSEP SQEELAAAKL QIGELSGKVK KLQYENRVLL 360
SNLQRCDLAS CQSTRPMLET DAEAGDSAQC VPAPLGETHE SHAVRLCRAR EAEVLPGLRE 420
QAALVSKAID VLVADANGFT AGLRLCLDNE CADFRLHEAP DNSEGPRDTK LIHAILVRLS 480
VLQQELNAFT RKADAVLGCS VKEQQESFSS LPPLGSQGLS KEILLAKDLG SDFQPPDFRD 540
LPEWEPRIRE AFRTGDLDSK PDPSRSFRPY RAEDNDSYAS EIKELQLVLA EAHDSLRGLQ 600
EQLSQERQLR KEEADNFNQK MVQLKEDQQR ALLRREFELQ SLSLQRRLEQ KFWSQEKNML 660
VQESQQFKHN FLLLFMKLRW FLKRWRQGKV LPSEGDDFLE VNSMKELYLL MEEEEINAQH 720
SDNKACTGDS WTQNTPNEYI KTLADMKVTL KELCWLLRDE RRGLTELQQQ FAKAKATWET 780
ERAELKGHTS QMELKTGKGA GERAGPDWKA ALQREREEQQ HLLAESYSAV MELTRQLQIS 840
ERNWSQEKLQ LVERLQGEKQ QVEQQVKELQ NRLSQLQKAA DPWVLKHSEL EKQDNSWKET 900
RSEKIHDKEA VSEVELGGNG LKRTKSVSSM SEFESLLDCS PYLAGGDARG KKLPNNPAFG 960
FVSSEPGDPE KDTKEKPGLS SRDCNHLGAL ACQDPPGRQM QRSYTAPDKT GIRVYYSPPV 1020
ARRLGVPVVH DKEGKIIIEP GFLFTTAKPK ESAEADGLAE SSYGRWLCNF SRQRLDGGSA 1080
GSPSAAGPGF PAALHDFEMS GNMSDDMKEI TNCVRQAMRS GSLERKVKST SSQTVGLASV 1140
GTQTIRTVSV GLQTDPPRSS LHGKAWSPRS SSLVSVRSKQ ISSSLDKVHS RIERPCCSPK 1200
YGSPKLQRRS VSKLDSSKDR SLWNLHQGKQ NGSAWARSTT TRDSPVLRNI NDGLSSLFSV 1260
VEHSGSTESV WKLGMSETRA KPEPPKYGIV QEFFRNVCGR APSPTSSAGE EGTKKPEPLS 1320
PASYHQPEGV ARILNKKAAK LGSSEEVRLT MLPQVGKDGV LRDGDGAVVL PNEDAVCDCS 1380
TQSLTSCFAR SSRSAIRHSP SKCRLHPSES SWGGEERALP PSE 1423 
Gene Ontology
 GO:0005615; C:extracellular space; IDA:UniProtKB.
 GO:0010506; P:regulation of autophagy; ISS:UniProtKB. 
Interpro
 IPR021507; DUF3166. 
Pfam
 PF11365; DUF3166 
SMART
  
PROSITE
  
PRINTS