UniProt Accession

 RIMN_ECOLI; P45748; Q2M6U7 

Genbank Protein ID

 U18997; U00096; AP009048 

Genbank Nucleotide ID

 AAA58079.1; AAC76307.1; BAE78009.1 

Protein Name

 tRNA threonylcarbamoyladenosine biosynthesis protein RimN 

Protein Synonyms/Alias

 Ribosome maturation factor RimN; t(6)A37 threonylcarbamoyladenosine biosynthesis protein RimN 

Gene Name

 rimN 

Gene Synonyms/Alias

 yrdC; b3282; JW3243 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
50	VMRLLELKQRPVDKG	acetylation	[1]
56	LKQRPVDKGLILIAA	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Binds ATP, and to fully modified tRNA(Thr) and partially modified tRNA(Thr). Could also be required for the maturation of 16S rRNA. Binds to double-stranded RNA but does not interact tightly with either of the ribosomal subunits, or the 70S particles. 

Sequence Annotation

 DOMAIN 7 190 YrdC-like.  

Keyword

 3D-structure; ATP-binding; Complete proteome; Cytoplasm; Nucleotide-binding; Reference proteome; Ribosome biogenesis; RNA-binding; rRNA processing; tRNA processing; tRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 190 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:EcoCyc.
 GO:0005524; F:ATP binding; IDA:EcoCyc.
 GO:0003725; F:double-stranded RNA binding; IDA:EcoCyc.
 GO:0000049; F:tRNA binding; IDA:EcoCyc.
 GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
 GO:0070526; P:threonylcarbamoyladenosine biosynthetic process; IDA:EcoCyc. 

Interpro

 IPR017945; DHBP_synth_RibB-like_a/b_dom.
 IPR023535; tRNA-t6A_RimN_(YrdC).
 IPR006070; YrdC-like_dom. 

Pfam

 PF01300; Sua5_yciO_yrdC 

SMART

  

PROSITE

 PS51163; YRDC 

PRINTS