CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002968
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nicotinate-nucleotide adenylyltransferase 
Protein Synonyms/Alias
 Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase 
Gene Name
 nadD 
Gene Synonyms/Alias
 ybeN; b0639; JW0634 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
78TLDERELKRNAPSYTacetylation[1]
90SYTAQTLKEWRQEQGacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). 
Sequence Annotation
  
Keyword
 3D-structure; ATP-binding; Complete proteome; NAD; Nucleotide-binding; Nucleotidyltransferase; Pyridine nucleotide biosynthesis; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 213 AA 
Protein Sequence
MKSLQALFGG TFDPVHYGHL KPVETLANLI GLTRVTIIPN NVPPHRPQPE ANSVQRKHML 60
ELAIADKPLF TLDERELKRN APSYTAQTLK EWRQEQGPDV PLAFIIGQDS LLTFPTWYEY 120
ETILDNAHLI VCRRPGYPLE MAQPQYQQWL EDHLTHNPED LHLQPAGKIY LAETPWFNIS 180
ATIIRERLQN GESCEDLLPE PVLTYINQQG LYR 213 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; IDA:EcoCyc.
 GO:0034628; P:de novo NAD biosynthetic process from aspartate; IMP:EcoCyc.
 GO:0034355; P:NAD salvage; IMP:EcoCyc. 
Interpro
 IPR004821; Cyt_trans-like.
 IPR005248; NAMN_adtrnsfrase.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF01467; CTP_transf_2 
SMART
  
PROSITE
  
PRINTS