CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008757
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphatidylinositol transfer protein alpha isoform 
Protein Synonyms/Alias
 PI-TP-alpha; PtdIns transfer protein alpha; PtdInsTP alpha 
Gene Name
 Pitpna 
Gene Synonyms/Alias
 Pitpn 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
105VITNEYMKEDFLIKIubiquitination[1]
153DRSQVLSKDYKAEEDubiquitination[1]
163KAEEDPAKFKSVKTGubiquitination[1]
179GPLGPNWKQELVNQKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes. 
Sequence Annotation
 BINDING 59 59 Phosphatidylinositol lipid headgroup (By
 BINDING 61 61 Phosphatidylinositol lipid headgroup (By
 BINDING 86 86 Phosphatidylinositol lipid headgroup (By
 BINDING 90 90 Phosphatidylinositol lipid headgroup (By
 BINDING 97 97 Phosphatidylinositol lipid headgroup (By
 BINDING 195 195 Phosphatidylinositol lipid headgroup (By
 MOD_RES 216 216 N6-acetyllysine (By similarity).  
Keyword
 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Lipid-binding; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 271 AA 
Protein Sequence
MVLLKEYRVI LPVSVDEYQV GQLYSVAEAS KNETGGGEGV EVLVNEPYEK DDGEKGQYTH 60
KIYHLQSKVP TFVRMLAPEG ALNIHEKAWN AYPYCRTVIT NEYMKEDFLI KIETWHKPDL 120
GTQENVHKLE PEAWKHVEAI YIDIADRSQV LSKDYKAEED PAKFKSVKTG RGPLGPNWKQ 180
ELVNQKDCPY MCAYKLVTVK FKWWGLQNKV ENFIHKQEKR LFTNFHRQLF CWLDKWVDLT 240
MDDIRRMEEE TKRQLDEMRQ KDPVKGMTAD D 271 
Gene Ontology
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0016021; C:integral to membrane; ISS:MGI.
 GO:0000062; F:fatty-acyl-CoA binding; IEA:Compara.
 GO:0035091; F:phosphatidylinositol binding; IEA:Compara.
 GO:0005543; F:phospholipid binding; ISO:MGI.
 GO:0070540; F:stearic acid binding; IEA:Compara.
 GO:0015914; P:phospholipid transport; IEA:Compara. 
Interpro
 IPR001666; PI_transfer.
 IPR023393; START-like_dom. 
Pfam
 PF02121; IP_trans 
SMART
  
PROSITE
  
PRINTS
 PR00391; PITRANSFER.