UniProt Accession

 RL23_ECOLI; P0ADZ0; P02424; Q2M6Y3 

Genbank Protein ID

 X02613; U18997; U00096; AP009048 

Genbank Nucleotide ID

 CAA26462.1; AAA58115.1; AAC76343.1; BAE77973.1 

Protein Name

 50S ribosomal protein L23 

Protein Synonyms/Alias

  

Gene Name

 rplW 

Gene Synonyms/Alias

 b3318; JW3280 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
26	KASTAMEKSNTIVLK	acetylation	[1]
33	KSNTIVLKVAKDATK	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor (PubMed:12226666) for Ffh binding to the ribosome (SRP54, PubMed:12756233 and PubMed:12702815) and to nascent polypeptide chains (PubMed:12756233). 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 100 AA 

Protein Sequence

Gene Ontology

 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0019843; F:rRNA binding; IEA:HAMAP.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:HAMAP. 

Interpro

 IPR012677; Nucleotide-bd_a/b_plait.
 IPR012678; Ribosomal_L23/L15e_core_dom.
 IPR001014; Ribosomal_L23/L25_CS.
 IPR013025; Ribosomal_L25/23. 

Pfam

 PF00276; Ribosomal_L23 

SMART

  

PROSITE

 PS00050; RIBOSOMAL_L23 

PRINTS