CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045337
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mitochondrial import inner membrane translocase subunit TIM50 
Protein Synonyms/Alias
  
Gene Name
 TIMM50 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
205YMDGHHVKDISCLNRubiquitination[1, 2]
224VVVVDCKKEAFRLQPubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 257 AA 
Protein Sequence
XAASAAVFSR LRSGLRLGSR GLCTRLATPP RRAPDQAAEI GSRGSTKAQG PQQQPGSEGP 60
SYAKKVALWL AGLLGAGGTV SVVYIFGNNP VDENGAKMII EPTSPCLLPD PLQEPYYQPP 120
YTLVLELTGV LLHPEWSLAT GWRFKKRPGI ETLFQQLAPL YEIVIFTSET GMTAFPLIDS 180
VDPHGFISYR LFRDATRYMD GHHVKDISCL NRDPARVVVV DCKKEAFRLQ PYNGVALRPW 240
DGNSDDRVLL DLSAFLK 257 
Gene Ontology
 GO:0005744; C:mitochondrial inner membrane presequence translocase complex; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:InterPro. 
Interpro
 IPR023214; HAD-like_dom.
 IPR004274; NIF.
 IPR027111; Tim50. 
Pfam
 PF03031; NIF 
SMART
 SM00577; CPDc 
PROSITE
 PS50969; FCP1 
PRINTS