CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039682
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tripartite motif-containing protein 46 
Protein Synonyms/Alias
  
Gene Name
 TRIM46 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
424RERLAISKDQRAVRSubiquitination[1]
488VGVGLESKLQESFQGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 633 AA 
Protein Sequence
MFPCPACQGD VELGERGLAG LFRNLTLERV VERYRQSVSV GGAILCQLCK PPPLEATKGC 60
TECRATFCNE CFKLFHPWGT QKAQHEPTLP TLSFRPKGLM CPDHKEEVTH YCKTCQRLVC 120
QLCRVRRTHS GHKITPVLSA YQALKDKLTK SLTYILGNQD TVQTQICELE EAVRHTEVSG 180
QQAKEEVSQL VRGLGAVLEE KRASLLQAIE ECQQERLARL SAQIQEHRSL LDGSGLVGYA 240
QEVLKETDQP CFVQAAKQLH NRIARATEAL QTFRPAASSS FRHCQLDVGR EMKLLTELNF 300
LRVPEAPVID TQRTFAYDQI FLCWRLPPHS PPAWHYTVEF RRTDVPAQPG PTRWQRREEV 360
RGTSALLENP DTGSVYVLRV RGCNKAGYGE YSEDVHLHTP PAPVLHFFLD SRWGASRERL 420
AISKDQRAVR SVPGLPLLLA ADRLLTGCHL SVDVVLGDVA VTQGRSYWAC AVDPASYLVK 480
VGVGLESKLQ ESFQGAPDVI SPRYDPDSGH DSGAEDATVE ASPPFAFLTI GMGKILLGSG 540
ASSNAGLTGR DGPTAGCTVP LPPRLGICLD YERGRVSFLD AVSFRGLLEC PLDCSGPVCP 600
AFCFIGGGAV QLQEPVGTKP ERKVTIGGFA KLD 633 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR008985; ConA-like_lec_gl_sf.
 IPR017903; COS_domain.
 IPR003961; Fibronectin_type3.
 IPR013783; Ig-like_fold.
 IPR000315; Znf_B-box. 
Pfam
 PF00643; zf-B_box 
SMART
 SM00336; BBOX
 SM00060; FN3 
PROSITE
 PS50188; B302_SPRY
 PS51262; COS
 PS50853; FN3
 PS50119; ZF_BBOX 
PRINTS