UniProt Accession

 E9PLG0_HUMAN; E9PLG0 

Genbank Protein ID

 AC093731; AC097377 

Genbank Nucleotide ID

  

Protein Name

 Flap endonuclease GEN homolog 1 

Protein Synonyms/Alias

  

Gene Name

 GEN1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
14	WQILEPVKQHIPLRN	ubiquitination	[1]
99	SRYGSSGKSWSQKTG	ubiquitination	[1]
111	KTGRSHFKSVLRECL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 126 AA 

Protein Sequence

Gene Ontology

 GO:0004518; F:nuclease activity; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 

Interpro

 IPR006084; XPG/Rad2.
 IPR006085; XPG_DNA_repair_N. 

Pfam

 PF00752; XPG_N 

SMART

 SM00485; XPGN 

PROSITE

  

PRINTS

 PR00853; XPGRADSUPER.