| Tag | Content |
|---|
| CPLM ID | CPLM-024669 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | F-box/WD repeat-containing protein 2 |
Protein Synonyms/Alias | F-box and WD-40 domain-containing protein 2; Protein MD6 |
Gene Name | Fbxw2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 298 | YILLSADKYEIKIWP | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity). |
Sequence Annotation | DOMAIN 54 101 F-box.
REPEAT 146 183 WD 1.
REPEAT 185 221 WD 2.
REPEAT 224 265 WD 3.
REPEAT 276 314 WD 4.
MOD_RES 298 298 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Reference proteome; Repeat; Ubl conjugation pathway; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 454 AA |
Protein Sequence | MERKDFETWL DNISVTFLSL TDLQKNETLD HLISLSGAVQ LRHLSNNLET LLKRDFLKLL 60
PLELSFYLLK WLDPQTLLTC CLVSKQWNKV ISACTEVWQT ACKNLGWQID DSVQDALHWK 120
KVYLKAILRM KQLEDHEAFE TSSLIGHSAR VYALYYKDGL LCTGSDDLSA KLWDVSTGQC 180
VYGIQTHTCA AVKFDEQKLV TGSFDNTVAC WEWSSGARTQ HFRGHTGAVF SVDYSDELDI 240
LVSGSADFAV KVWALSAGTC LNTLTGHTEW VTKVVLQQCK VKSLLHSPGD YILLSADKYE 300
IKIWPIGREI NCKCLKTLSV SEDRSICLQP RLHFDGKYIV CSSALGLYQW DFASYDILRV 360
IKTPEVANLA LLGFGDVFAL LFDNHYLYIM DLRTESLISR WPLPEYRKSK RGSSFLAGEA 420
SWLNGLDGHN DTGLVFATSM PDHSIHLVLW KEHG 454 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |