| Tag | Content |
|---|
| CPLM ID | CPLM-018613 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 2-acylglycerol O-acyltransferase 1 |
Protein Synonyms/Alias | Acyl-CoA:monoacylglycerol acyltransferase 1; MGAT1; Diacylglycerol acyltransferase 2-like protein 1; Monoacylglycerol O-acyltransferase 1 |
Gene Name | Mogat1 |
Gene Synonyms/Alias | Dgat2l1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 234 | FGENDLYKQINNPKG | ubiquitination | [1] | | 240 | YKQINNPKGSWLRTI | ubiquitination | [1] | | 314 | QTYLEELKKLFNEHK | ubiquitination | [1] | | 323 | LFNEHKGKYGIPEHE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine. |
Sequence Annotation | CARBOHYD 180 180 N-linked (GlcNAc...) (Potential). |
Keyword | Acyltransferase; Complete proteome; Endoplasmic reticulum; Glycerol metabolism; Glycoprotein; Lipid biosynthesis; Lipid metabolism; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 335 AA |
Protein Sequence | MMVEFAPLNT PLARCLQTAA VLQWVLSFLL LVQVCIGIMV MLVLYNYWFL YIPYLVWFYY 60
DWRTPEQGGR RWNWVQSWPV WKYFKEYFPI CLVKTQDLDP GHNYIFGFHP HGIFVPGAFG 120
NFCTKYSDFK KLFPGFTSYL HVAKIWFCFP LFREYLMSNG PVSVSKESLS HVLSKDGGGN 180
VSIIVLGGAK EALEAHPGTF TLCIRQRKGF VKMALTHGAS LVPVFSFGEN DLYKQINNPK 240
GSWLRTIQDA MYDSMGVALP LIYARGIFQH YFGIMPYRKL IYTVVGRPIP VQQTLNPTSE 300
QIEELHQTYL EELKKLFNEH KGKYGIPEHE TLVFK 335 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IDA:MGI. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0016020; C:membrane; IDA:MGI. GO:0003846; F:2-acylglycerol O-acyltransferase activity; IDA:MGI. GO:0004144; F:diacylglycerol O-acyltransferase activity; IDA:MGI. GO:0006651; P:diacylglycerol biosynthetic process; IDA:MGI. GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW. GO:0019432; P:triglyceride biosynthetic process; IEA:UniProtKB-UniPathway. |
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SMART | |
PROSITE | |
PRINTS | |