| Tag | Content |
|---|
| CPLM ID | CPLM-026191 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform |
Protein Synonyms/Alias | |
Gene Name | PIK3CD |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 46 | NANLSTIKQLLWHRA | ubiquitination | [1] | | 557 | HEKDLVWKLRHEVQE | ubiquitination | [1] | | 865 | IANIQLNKSNMAATA | ubiquitination | [1] |
|
Reference | [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties. Chen Z, Zhou Y, Song J, Zhang Z. Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [ PMID: 23603789] |
Functional Description | |
Sequence Annotation | |
Keyword | ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1068 AA |
Protein Sequence | MPPGVDCPME FWTKEENQSV VVDFLLPTGV YLNFPVSRNA NLSTIKQLLW HRAQYEPLFH 60
MLSGPEAYVF TCINQTAEQQ ELEDEQRRLC DVQPFLPVLR LVAREGDRVK KLINSQISLL 120
IGKGLHEFDS LCDPEVNDFR AKMCQFCEEA AARRQQLGWE AWLQYSFPLQ LEPSAQTWGP 180
GTLRLPNRAL LVNVKFEGSE ESFTFQVSTK DVPLALMACA LRKKATVFRQ PLVEQPEDYT 240
LQVNGRHEYL YGSYPLCQFQ VQKPRAKPPP IPAKKPSSVS LWSLEQPFRI ELIQGSKVNA 300
DERMKLVVQA GLFHGNEMLC KTVSSSEVSV CSEPVWKQRL EFDINICDLP RMARLCFALY 360
AVIEKAKKAR STKKKSKKAD CPIAWANLML FDYKDQLKTG ERCLYMWPSV PDEKGELLNP 420
TGTVRSNPNT DSAAALLICL PEVAPHPVYY PALEKLPGGM LLASREWRPE LLWMRLHAED 480
SAPSRMIGVA MPGLGVLPGL VQAPGDAECS RLLQILELGR HSECVHVTEE EQLQLREILE 540
RRGSGELYEH EKDLVWKLRH EVQEHFPEAL ARLLLVTKWN KHEDVAQMLY LLCSWPELPV 600
LSALELLDFS FPDCHVGSFA IKSLRKLTDD ELFQYLLQLV QVLKYESYLD CELTKFLLDR 660
ALANRKIGHF LFWHLRSEMH VPSVALRFGL ILEAYCRGST HHMKVLMKQG EALSKLKALN 720
DFVKLSSQKT PKPQTKELMH LCMRQEAYLE ALSHLQSPLD PSTLLAEVCV EQCTFMDSKM 780
KPLWIMYSNE EAGSGGSVGI IFKNGDDLRQ DMLTLQMIQL MDVLWKQEGL DLRMTPYGCL 840
PTGDRTGLIE VVLRSDTIAN IQLNKSNMAA TAAFNKDALL NWLKSKNPGE ALDRAIEEFT 900
LSCAGYCVAT YVLGIGDRHS DNIMIRESGQ LFHIDFGHFL GNFKTKFGIN RERVPFILTY 960
DFVHVIQQGK TNNSEKFERF RGYCERAYTI LRRHGLLFLH LFALMRAAGL PELSCSKDIQ 1020
YLKDSLALGK TEEEALKHFR VKFNEALRES WKTKVNWLAH NVSKDNRQ 1068 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0016301; F:kinase activity; IEA:UniProtKB-KW. GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |