CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026857
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Four and a half LIM domains 1 
Protein Synonyms/Alias
 Four and a half LIM domains 1, isoform CRA_b; Four and a half LIM domains protein 1 
Gene Name
 Fhl1 
Gene Synonyms/Alias
 rCG_39239 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
38QGKKYVQKDGRHCCLacetylation[1]
61NTCVECRKPISADAKacetylation[1]
68KPISADAKEVHYKNRacetylation[1]
134GDQNVEYKGTIWHKDacetylation[1]
176CHETKFAKHCVKCNKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; LIM domain; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 296 AA 
Protein Sequence
MASQRHSGPS SYKVGTMSEK FDCHYCRDPL QGKKYVQKDG RHCCLKCFDK FCANTCVECR 60
KPISADAKEV HYKNRYWHDT CFRCAKCLHP LASETFVSKD GKILCNKCAT REDSPRCKGC 120
FKAIVAGDQN VEYKGTIWHK DCFTCSNCKQ VIGTGSFFPK GEDFYCVTCH ETKFAKHCVK 180
CNKAITSGGI TYQDQPWHAE CFVCVTCSKK LAGQRFTAVE DQYYCVDCYK NFVAKKCAGC 240
KNPITGFGKG SSVVAYEGQS WHDYCFHCKK CSVNLANKRF VFHNEQVYCP DCAKKL 296 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0030308; P:negative regulation of cell growth; IEA:Compara.
 GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IEA:Compara.
 GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IEA:Compara.
 GO:0043268; P:positive regulation of potassium ion transport; IEA:Compara.
 GO:0003254; P:regulation of membrane depolarization; IEA:Compara.
 GO:1901016; P:regulation of potassium ion transmembrane transporter activity; IEA:Compara. 
Interpro
 IPR001781; Znf_LIM. 
Pfam
 PF00412; LIM 
SMART
 SM00132; LIM 
PROSITE
 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2 
PRINTS