CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027503
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Growl, isoform B 
Protein Synonyms/Alias
  
Gene Name
 lost 
Gene Synonyms/Alias
 growl; CG14648; Dmel_CG14648 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
88DRVLHEFKELALLADacetylation[1]
135LRVQDIQKFRSEIGLacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 535 AA 
Protein Sequence
EYPCSRGAGA RFSHFLAQPI EPTKRSLRVQ TWKKIQEGKV GIGFNNIFNR IPSFVGADKA 60
AALFANEEEF KKAQHIKVNI DRVLHEFKEL ALLADKSVYL PSTRESSALC LKVDVLADAT 120
EEQKKEALRV QDIQKFRSEI GLDSGLKLDI VVIGSVVVSR EGYRIGRGNG FADLDIGLLI 180
ELGAITPKTI IVTIVHDMQV VDSLPPNLFQ KYDTPVDIIA TPTEIIRVPK RLSFPNGVYW 240
ELLSERRLKI LPVLQQLKER EEKAGKSISL KEEDTDVEQH QNNRRRRGPV RRRIQRGNPG 300
RTTSQTDNEQ PQGETAQKRT PRRKGRFVNR RRRTTKSEGD QSGVEAGAKT DDRKLPEAGT 360
DERRSKKNKN SDFCIKLTNL SRDIRVKDLK SELRKRECTP MSISWKGHFG KCFLHFGNRK 420
GVPSTQDDMD KVLKSLNDLS LTITTGGETA PAAAAGEGGE KAESAETATP VQTKTILVNV 480
ELIQFGEKKS ASSTGANAGA GEDGKADAQN GGEAVTVAGG DVGGARIEAV DTTTV 535 
Gene Ontology
 GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.
 GO:0005737; C:cytoplasm; IDA:FlyBase.
 GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
 GO:0030272; F:5-formyltetrahydrofolate cyclo-ligase activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
 GO:0000398; P:mRNA splicing, via spliceosome; IC:FlyBase.
 GO:0007277; P:pole cell development; IGI:FlyBase.
 GO:0045451; P:pole plasm oskar mRNA localization; IGI:FlyBase. 
Interpro
 IPR002698; FTHF_cligase.
 IPR024185; FTHF_cligase-like. 
Pfam
 PF01812; 5-FTHF_cyc-lig 
SMART
  
PROSITE
  
PRINTS