UniProt Accession

 B7Z1W5_HUMAN; B7Z1W5 

Genbank Protein ID

 AC083973; AC107885; AK294025 

Genbank Nucleotide ID

 BAH11651.1 

Protein Name

 DNA polymerase beta 

Protein Synonyms/Alias

 cDNA FLJ57297, highly similar to DNA polymerase beta (EC 2.7.7.7) 

Gene Name

 POLB 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
76	FITDTLSKGETKFMG	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 181 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003684; F:damaged DNA binding; IEA:Compara.
 GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:Compara.
 GO:0008219; P:cell death; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0006290; P:pyrimidine dimer repair; IEA:Compara.
 GO:0045471; P:response to ethanol; IEA:Compara. 

Interpro

 IPR002054; DNA-dir_DNA_pol_X.
 IPR019843; DNA_pol-X_BS.
 IPR022312; DNA_pol_X.
 IPR002008; DNA_pol_X_beta-like. 

Pfam

  

SMART

 SM00483; POLXc 

PROSITE

 PS00522; DNA_POLYMERASE_X 

PRINTS

 PR00869; DNAPOLX.
 PR00870; DNAPOLXBETA.