CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027136
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA1547 protein 
Protein Synonyms/Alias
  
Gene Name
 Tle3 
Gene Synonyms/Alias
 mKIAA1547 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
845KWFVSTGKDNLLNAWubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 897 AA 
Protein Sequence
LTREGTGESP FPQTPGLGIP HWSRQGADDV HADPASDTVH AAGGRRPAAA GRALGAQSAS 60
PPTTLPLAPP LFVCTWGARP TLGFRCESGL GGPGASSRFP GRPPLGLASP LPRTSPARAL 120
SASKLSESRP LPAMYPQGRH PAPHQPGQPG FKFTVAESCD RIKDEFQFLQ AQYHSLKVEY 180
DKLANEKTEM QRHYVMYYEM SYGLNIEMHK QTEIAKRLNT ILAQIMPFLS QEHQQQVAQA 240
VERAKQVTMT ELNAIIGQQQ LQAQHLSHAT HGPPVQLPPH PSGLQPPGIP PVTGSSSGLL 300
ALGALGSQAH LAVKDEKNHH ELDHRERESS TNNSVSPSES LRASEKHRGS ADYSMEAKKR 360
KAEEKDSLSR YDSDGDKSDD LVVDVSNEDP ATPRVSPAHS PPENGLDKAR GLKKDAPTSP 420
ASVASSSSTP SSKTKDLGHN DKSSTPGLKS NTPTPRNDAP TPGTSTTPGL RSMPGKPPGM 480
DPIASALRTP ITLTSSYPAP FAMMSHHEMN GSLTSPSAYA GLHNIPSQMS AAAAAAAAAY 540
GRSPMVGFDP HPPMRATGLP SSLASIPGGK PAYSFHVSAD GQMQPVPFPH DALAGPGIPR 600
HARQINTLSH GEVVCAVTIS NPTRHVYTGG KGCVKIWDIS QPGSKSPISQ LDCLNRDNYI 660
RSCKLLPDGR TLIVGGEAST LTIWDLASPT PRIKAELTSS APACYALAIS PDAKVCFSCC 720
SDGNIAVWDL HNQTLVRQFQ GHTDGASCID ISHDGTKLWT GGLDNTVRSW DLREGRQLQQ 780
HDFTSQIFSL GYCPTGEWLA VGMESSNVEV LHHTKPDKYQ LHLHESCVLS LKFAYCGKWF 840
VSTGKDNLLN AWRTPYGASI FQSKESSSVL SCDISADDKY IVTGSGDKKA TVYEVIY 897 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR005617; Groucho/TLE_N.
 IPR009146; Groucho_enhance.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF03920; TLE_N
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR01850; GROUCHOFAMLY.