| Tag | Content |
|---|
| CPLM ID | CPLM-004895 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mimecan |
Protein Synonyms/Alias | Osteoglycin; Osteoinductive factor; OIF |
Gene Name | OGN |
Gene Synonyms/Alias | OIF; SLRR3A |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 281 | GNPIVLGKHPNSFIC | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. |
Sequence Annotation | REPEAT 112 131 LRR 1.
REPEAT 132 155 LRR 2.
REPEAT 156 179 LRR 3.
REPEAT 180 199 LRR 4.
REPEAT 200 225 LRR 5.
REPEAT 226 246 LRR 6.
REPEAT 247 277 LRR 7.
CARBOHYD 80 80 O-linked (GalNAc...).
CARBOHYD 214 214 N-linked (GlcNAc...) (Potential).
CARBOHYD 258 258 N-linked (GlcNAc...).
DISULFID 255 288 By similarity. |
Keyword | Complete proteome; Direct protein sequencing; Disulfide bond; Extracellular matrix; Glycoprotein; Growth factor; Leucine-rich repeat; Reference proteome; Repeat; Secreted; Signal. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 298 AA |
Protein Sequence | MKTLQSTLLL LLLVPLIKPA PPTQQDSRII YDYGTDNFEE SIFSQDYEDK YLDGKNIKEK 60
ETVIIPNEKS LQLQKDEAIT PLPPKKENDE MPTCLLCVCL SGSVYCEEVD IDAVPPLPKE 120
SAYLYARFNK IKKLTAKDFA DIPNLRRLDF TGNLIEDIED GTFSKLSLLE ELSLAENQLL 180
KLPVLPPKLT LFNAKYNKIK SRGIKANAFK KLNNLTFLYL DHNALESVPL NLPESLRVIH 240
LQFNNIASIT DDTFCKANDT SYIRDRIEEI RLEGNPIVLG KHPNSFICLK RLPIGSYF 298 |
Gene Ontology | GO:0005615; C:extracellular space; IDA:BHF-UCL. GO:0005796; C:Golgi lumen; TAS:Reactome. GO:0043202; C:lysosomal lumen; TAS:Reactome. GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. GO:0005975; P:carbohydrate metabolic process; TAS:Reactome. GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome. GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome. GO:0048662; P:negative regulation of smooth muscle cell proliferation; ISS:UniProtKB. |
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Pfam | |
SMART | |
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PRINTS | |