CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010137
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Probable inorganic polyphosphate/ATP-NAD kinase 
Protein Synonyms/Alias
 Poly(P)/ATP NAD kinase 
Gene Name
 ppnK 
Gene Synonyms/Alias
 MPN_267; MP566 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
200TQVEFVVKKAFNPQQacetylation[1]
201QVEFVVKKAFNPQQFacetylation[1]
257KLKSTFIKQS*****acetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819
Functional Description
 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity). 
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Cytoplasm; Kinase; NAD; NADP; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 259 AA 
Protein Sequence
MKYKIFASTT PQTEPVLQKL KQVLKGCEAV EKGFDYLFVL GGDGFFVSTV ANYNCHNCRV 60
VGINTGHLGF YTSFNEKDLD DNFLQKLQQC HFQRISLLEV SVNGQQHLVL NELAVYTNTA 120
YPINIFIDGE AWEFYRGSGL LIGPRTGSTA LAKSAKGAVI FPGIDVLQII EMNPLLHPNQ 180
VTIQSPIILP KETQVEFVVK KAFNPQQFPT FYCDGRKLEL PNADTTLALK LVQSTPMFNI 240
SLKTQDFINK LKSTFIKQS 259 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:HAMAP.
 GO:0003951; F:NAD+ kinase activity; IEA:HAMAP.
 GO:0019674; P:NAD metabolic process; IEA:InterPro.
 GO:0006741; P:NADP biosynthetic process; IEA:InterPro. 
Interpro
 IPR017438; ATP-NAD_kinase_dom_1.
 IPR016064; ATP-NAD_kinase_PpnK-typ.
 IPR017437; ATP-NAD_kinase_PpnK-typ_all-b.
 IPR002504; PolyP/ATP_NADK_prd. 
Pfam
 PF01513; NAD_kinase 
SMART
  
PROSITE
  
PRINTS