CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000673
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Beta-1,4-galactosyltransferase 5 
Protein Synonyms/Alias
 Beta-1,4-GalTase 5; Beta4Gal-T5; b4Gal-T5; Beta-1,4-GalT II; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5 
Gene Name
 B4GALT5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
285LTVEQFRKINGFPNAubiquitination[1]
323RPEGDTGKYKSIPHHubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. 
Sequence Annotation
 METAL 236 236 Manganese (By similarity).
 METAL 329 329 Manganese (By similarity).
 CARBOHYD 77 77 N-linked (GlcNAc...) (Potential).
 CARBOHYD 81 81 N-linked (GlcNAc...) (Potential).
 CARBOHYD 90 90 N-linked (GlcNAc...) (Potential).
 CARBOHYD 111 111 N-linked (GlcNAc...) (Potential).
 CARBOHYD 128 128 N-linked (GlcNAc...) (Potential).
 CARBOHYD 364 364 N-linked (GlcNAc...) (Potential).
 CARBOHYD 373 373 N-linked (GlcNAc...) (Potential).
 DISULFID 114 158 By similarity.
 DISULFID 229 248 By similarity.  
Keyword
 Complete proteome; Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus; Manganese; Membrane; Metal-binding; Polymorphism; Reference proteome; Signal-anchor; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 388 AA 
Protein Sequence
MRARRGLLRL PRRSLLAALF FFSLSSSLLY FVYVAPGIVN TYLFMMQAQG ILIRDNVRTI 60
GAQVYEQVLR SAYAKRNSSV NDSDYPLDLN HSETFLQTTT FLPEDFTYFA NHTCPERLPS 120
MKGPIDINMS EIGMDYIHEL FSKDPTIKLG GHWKPSDCMP RWKVAILIPF RNRHEHLPVL 180
FRHLLPMLQR QRLQFAFYVV EQVGTQPFNR AMLFNVGFQE AMKDLDWDCL IFHDVDHIPE 240
SDRNYYGCGQ MPRHFATKLD KYMYLLPYTE FFGGVSGLTV EQFRKINGFP NAFWGWGGED 300
DDLWNRVQNA GYSVSRPEGD TGKYKSIPHH HRGEVQFLGR YALLRKSKER QGLDGLNNLN 360
YFANITYDAL YKNITVNLTP ELAQVNEY 388 
Gene Ontology
 GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
 GO:0000139; C:Golgi membrane; TAS:Reactome.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0008378; F:galactosyltransferase activity; TAS:ProtInc.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
 GO:0016266; P:O-glycan processing; TAS:Reactome.
 GO:0043687; P:post-translational protein modification; TAS:Reactome.
 GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome. 
Interpro
 IPR003859; Galactosyl_T_2_met. 
Pfam
 PF02709; Glyco_transf_7C 
SMART
  
PROSITE
  
PRINTS
 PR02050; B14GALTRFASE.