CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008588
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 tRNA acetyltransferase TAN1 
Protein Synonyms/Alias
  
Gene Name
 TAN1 
Gene Synonyms/Alias
 YGL232W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
100LKGEETGKDLSSGETacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Probable tRNA acetyltransferase required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs. Binds RNA. 
Sequence Annotation
 DOMAIN 146 259 THUMP.
 MOD_RES 72 72 Phosphoserine.  
Keyword
 Acyltransferase; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome; RNA-binding; Transferase; tRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MGEKRNRNGK DANSQNRKKF KVSSGFLDPG TSGIYATCSR RHERQAAQEL QLLFEEKFQE 60
LYGDIKEGED ESENDEKKDL SIEDQIKKEL QELKGEETGK DLSSGETKKK DPLAFIDLNC 120
ECVTFCKTRK PIVPEEFVLS IMKDLADPKN MVKRTRYVQK LTPITYSCNA KMEQLIKLAN 180
LVIGPHFHDP SNVKKNYKFA VEVTRRNFNT IERMDIINQV VKLVNKEGSE FNHTVDLKNY 240
DKLILVECFK SNIGMCVVDG DYKTKYRKYN VQQLYESKFR KDEDKSVKQ 289 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
 GO:0006400; P:tRNA modification; IMP:SGD. 
Interpro
 IPR004114; THUMP. 
Pfam
 PF02926; THUMP 
SMART
 SM00981; THUMP 
PROSITE
 PS51165; THUMP 
PRINTS