| Tag | Content |
|---|
| CPLM ID | CPLM-023356 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pre-mRNA-splicing factor Slu7 |
Protein Synonyms/Alias | |
Gene Name | Slu7 |
Gene Synonyms/Alias | CG1420 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 261 | NSAYYDPKTRSMRDN | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron (By similarity). |
Sequence Annotation | ZN_FING 116 133 CCHC-type.
MOD_RES 207 207 Phosphoserine.
MOD_RES 216 216 Phosphotyrosine. |
Keyword | Complete proteome; Metal-binding; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Spliceosome; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 574 AA |
Protein Sequence | MSSGPMRTPV SQIILSKHDQ DAEEEPKKKS REDWRKAKEL EEARKAGTAP AAVDEEGRDI 60
NPHIPQYISN APWYYGSAGP TLKHQRPQHE DEQGQLDKRA PKGLNTARII TKFRKGACEN 120
CGAVTHKRKD CLERPRKVQA KYAESIVVHD EHLVNEAAVN YDEKRDRWSS YDPANHREII 180
EEYEKVEEAK RQLKAEKLKN DPDAEISDEE GNEDKYVDEV DMPGTKVDSK QRITVRNLRI 240
REDTAKYLRN LDPNSAYYDP KTRSMRDNPN PAVPEEEAEF AGENFVRFSG DTTAQATAQL 300
FAWEAHGKGV DVHLLAEPTK LELLQKEYEQ KKEQFKSSTK THIVEKYGGE EHLQVPPKSL 360
LLAQTEEYIE YSRSGKVIKG VEKPKARSIY EEDVYINNHT TVWGSFWNAG RWGYKCCKSF 420
IKNSYCVGMQ EPEGYSEHHS TSSTAAATTE PAAQSQFKVP EVPPERPTSE VDSASSSEPS 480
SSEEEEVKPE KKKTKKKSKK REKKKKAKEQ RKQKGKNKET KDKDKTKEKD IPEELDDRKR 540
AYNSMYDVKA PTEDEIEEWK KKRPRAEDPM LQFM 574 |
Gene Ontology | GO:0016607; C:nuclear speck; ISS:UniProtKB. GO:0005681; C:spliceosomal complex; ISS:FlyBase. GO:0030628; F:pre-mRNA 3'-splice site binding; ISS:UniProtKB. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0007052; P:mitotic spindle organization; IMP:FlyBase. GO:0000389; P:mRNA 3'-splice site recognition; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |