| Tag | Content |
|---|
| CPLM ID | CPLM-010593 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | E3 ubiquitin-protein ligase hrd-like protein 1 |
Protein Synonyms/Alias | |
Gene Name | hrdl-1 |
Gene Synonyms/Alias | F26E4.11 |
Created Date | July 27, 2013 |
Organism | Caenorhabditis elegans |
NCBI Taxa ID | 6239 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 313 | LSRHRNHKKIFEHIE | ubiquitination | [1] |
|
Reference | [1] Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1. Crowe E, Candido EP. Dev Biol. 2004 Jan 15;265(2):446-59. [ PMID: 14732404] |
Functional Description | Proposed to have a role in neuroprotection. |
Sequence Annotation | DOMAIN 432 474 CUE.
ZN_FING 335 373 RING-type; atypical.
CARBOHYD 53 53 N-linked (GlcNAc...). |
Keyword | Complete proteome; Glycoprotein; Membrane; Metal-binding; Reference proteome; Transmembrane; Transmembrane helix; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 564 AA |
Protein Sequence | MGVVNLLSRS SFPSVDSYLA LSVLVAIVAS VTVFTTFRSQ PELQKLIEEE LRNNTRLSSA 60
YGLNIEALSG HTFFQIAHYI LSDTTLIWVA INSYFAILAV CTRLIIKLTF KELARQEENV 120
ARQAFFCYVL LTIVYLSVVI GPQKGHRVMP WMIWGGICAF LSHLQFITCQ RLKHISPSCD 180
RGSQKISFLS LFLFFVSIAM TFLISRFQHH LTWQPAVLLY FDCLLAVFRS TYILFRCISS 240
SRVFSFNPDS VRHFNYWLEL ITNFVCELIQ MLSFAQLLAF SPGLNLTSIF FLYHMKLTYN 300
CMTEQLSRHR NHKKIFEHIE RSYPSVKCAN GDDRCVVCWE LLGTSRRLPC SHQFHDWCLM 360
WWLAQDSSCP TCRCTIPSPQ DQIRQPPEVG NSTRLRFNGG SFGFVHFPAF TLEVAANFGP 420
FFGRAAEPTE EQLQTMLEQV REMFPQMSVD IIMTDLRQSG SAQSTIENIL EGRIGMNASF 480
MPGGVLDDEL SDESENEIEY EEPAEIVQEP DNGRQRTWTK LSSSSGDEDL SYYEIQRAKM 540
IETYRRKYLE SDKAADLRAM GITE 564 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0035264; P:multicellular organism growth; IGI:WormBase. GO:1901214; P:regulation of neuron death; IMP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |