CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028150
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 D-Importin 7/RanBP7 
Protein Synonyms/Alias
 FI03666p; Moleskin 
Gene Name
 msk 
Gene Synonyms/Alias
 dim-7; msk-RA; CG7935; Dmel_CG7935 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
286PSNVVSEKYQKFAEWacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1049 AA 
Protein Sequence
MEAQKLTELL RATIDPNPEQ RKAAEDQLAQ IHKIIGFVPT ILQIVMQTTV EQPVRQAGAV 60
YLKNLINSSW SDHEAKPGEP IPFSIHEQDR AMIRGAIVDA IVHAPELIRV QLSVCVNHII 120
KSDFPGRWPQ VVDSISIYLQ NQDVNGWNGA LVTMYQLVKT YEYKRHEERT PLNEAMNLLL 180
PMIYQLMVRL LAEQSEQSVL LQKQILKIYY ALTQYTLPLD LITKEIFSQW MEICRQVADR 240
AVPDSSHLDD DERTEFPYWK TKKWALHIMV RMFERYGSPS NVVSEKYQKF AEWYLPTFSQ 300
GVLEVLLKIL DQYRNRVYVS PRVLTDVLNY LKNAVSHAYT WKLIKPHMVA VIQDVIFPIM 360
SFTDSDQELW ESDPYEYIRL KFDIFEDYAT PVPAAQSLLH SMCKKRKGIL PKAMATIMQI 420
ITSPNADNKQ KDGALHMIGT LADVLLKKAS YRDQVESMLT TYVFPEFQNP AGHMRARACW 480
VLHYFCDVQI KNPQVLAEIM RLTTNALLTD KELPVKVEAA IGLQMFISSQ DEAPQYVEAQ 540
IKEITKELLT IIRETENEDL TNVMQKIVCT FTEQLLPVAT EICQHLATTF SQVLESEEGS 600
DEKAITAMSL LNTIETLLSV MEEHPDVLLN LHPIVINVVG HIFQHNITDF YEETFSLVYD 660
LTAKAISPEM WQMLELIYQV FKKDGIDYFI DIMPALHNYV TVDTPAFLSN PNRLLAILDM 720
CKTMLTSSPG EDPECHAAKL MEVIILQCKG QIDSVIHMFV ELALSRLTRE VQSSELRTMC 780
LQVVIAALYY NPQLLLSILD KMSQQNNDSI SAHFIKQWLH DTDCFLGIHD RKLCVLGLCT 840
LISLGEAKPQ VLSEVAGKIV PALILLFDGL KRAYESRAQE EEEDEEEEDG DDCEEALSSD 900
EDDMDEMAPD YLDKLAEFAK TKGNESGFEV KAEIKDDDAD SDGDAEESVG DLNETGLESF 960
TTPIDDEENE SAIDEYWTFK EVITALSAQD QAWYALLTSN LTPEQAKALQ EVVVTADQRK 1020
AAKESKLIEK QGGFAFPQTA VPTSFKFGS 1049 
Gene Ontology
 GO:0005938; C:cell cortex; IDA:FlyBase.
 GO:0005643; C:nuclear pore; IEA:InterPro.
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0008283; P:cell proliferation; IMP:FlyBase.
 GO:0042675; P:compound eye cone cell differentiation; IMP:FlyBase.
 GO:0007173; P:epidermal growth factor receptor signaling pathway; IGI:FlyBase.
 GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.
 GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.
 GO:0046331; P:lateral inhibition; IMP:FlyBase.
 GO:0000189; P:MAPK import into nucleus; IMP:FlyBase.
 GO:0043524; P:negative regulation of neuron apoptotic process; IMP:FlyBase.
 GO:0016318; P:ommatidial rotation; IMP:FlyBase.
 GO:0045465; P:R8 cell differentiation; IMP:FlyBase.
 GO:0042052; P:rhabdomere development; IMP:FlyBase.
 GO:0035311; P:wing cell fate specification; IMP:FlyBase. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR013713; Exportin/Importin_Cse1-like.
 IPR001494; Importin-beta_N. 
Pfam
 PF08506; Cse1
 PF03810; IBN_N 
SMART
 SM00913; IBN_N 
PROSITE
 PS50166; IMPORTIN_B_NT 
PRINTS