CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041882
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized protein 
Protein Synonyms/Alias
 Zinc finger protein 766 
Gene Name
 ZNF766 
Gene Synonyms/Alias
 LOC90321; hCG_1811957 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
46KCLDPVQKALYRDVMubiquitination[1]
93ENEMKVAKNPDRWEGubiquitination[1]
102PDRWEGIKDINTGRSubiquitination[1]
153YECNQVQKFISHSSSubiquitination[1]
172QRIYSGVKTHIFNKHubiquitination[1, 2]
242CGKTVRDKSGLAEHWubiquitination[1]
287HTGESPYKCNECGKVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 471 AA 
Protein Sequence
MLCEGEAQKR KAEESGMPLT QGHLTFRDVA IEFSQEEWKC LDPVQKALYR DVMLENYRNL 60
VSLGICLPDL SIISMMKQRT EPWTVENEMK VAKNPDRWEG IKDINTGRSC AVRSKAGNKP 120
ITNQLGLTFQ LPLPELEIFQ GEGKIYECNQ VQKFISHSSS VSPLQRIYSG VKTHIFNKHR 180
NDFVDFPLLS QEQKAHIRRK PYECNEQGKV FRVSSSLPNH QVIHTADKPN RCHECGKTVR 240
DKSGLAEHWR IRTGEKPYKC KECGKLFNRI AYLARHEKVH TGESPYKCNE CGKVFSRITY 300
LVRHQKIHTR EKPHKCNKCG KVYSSSSYLA QHWRIHTGEK LYKCNKCGKE FSGHSSLTTH 360
LLIHTGEKPY KCKECDKAFR HKFSLTVHQR NHNGEKPYKC HECGKVFTQV SHLARHQKIH 420
TGEKPYKCNE CGKVFTQNSH LANHQRIHTG EKPYKCHVCG LSLWSGKESV R 471 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS