CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003690
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Putative upstream-binding factor 1-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 UBTFL1 
Gene Synonyms/Alias
 C11orf27 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
278SQAEELQKQYKVKLDacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development (By similarity). 
Sequence Annotation
 DNA_BIND 100 168 HMG box 1.
 DNA_BIND 222 288 HMG box 2.  
Keyword
 Complete proteome; Cytoplasm; Developmental protein; DNA-binding; Nucleus; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 393 AA 
Protein Sequence
MALPRSQGHW SNKDILRLLE CMENNRPSDD NSTFSSTQSH MDWGKVAFKN FSGEMCRLKW 60
LEISCNLRKF GTLKELVLEA KKCVKKMNKS QKYRNGPDFP KRPLTAYNRF FKESWPQYSQ 120
MYPGMRSQEL TKILSKKYRE LPEQMKQKYI QDFRKEKQEF EEKLARFREE HPDLVQKAKK 180
SSVSKRTQNK VQKKFQKNIE EVRSLPKTDR FFKKVKFHGE PQKPPMNGYH KFHQDSWSSK 240
EMQHLSVRER MVEIGRRWQR IPQSQKDHFK SQAEELQKQY KVKLDLWLKT LSPENYAAYK 300
ESTYAKGKNM AMTGGPDPRL KQADPQSSSA KGLQEGFGEG QGLQAAGTDS SQTIWVNCHV 360
SMEPEENRKK DREKEESSNS SDCSSGEEIE VDV 393 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. 
Interpro
 IPR009071; HMG_box_dom. 
Pfam
 PF00505; HMG_box 
SMART
 SM00398; HMG 
PROSITE
 PS50118; HMG_BOX_2 
PRINTS