UniProt Accession

 D6RAL1_HUMAN; D6RAL1 

Genbank Protein ID

 AC093214 

Genbank Nucleotide ID

  

Protein Name

 Ribosome-releasing factor 2, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 GFM2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
154	PRICFLNKMDKTGAS	ubiquitination	[1]
157	CFLNKMDKTGASFKY	ubiquitination	[1]
163	DKTGASFKYAVESIR	ubiquitination	[1]
176	IREKLKAKPLLLQLP	ubiquitination	[1, 2]
188	QLPIGEAKTFKGVVD	ubiquitination	[1]
191	IGEAKTFKGVVDVVM	acetylation	[3]
199	GVVDVVMKEKLLWNC	ubiquitination	[1, 2]
201	VDVVMKEKLLWNCNS	ubiquitination	[1]
217	DGKDFERKPLLEMND	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 285 AA 

Protein Sequence

Gene Ontology

 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 

Interpro

 IPR000795; EF_GTP-bd_dom.
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom. 

Pfam

 PF00009; GTP_EFTU 

SMART

  

PROSITE

  

PRINTS