CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032048
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transporter 
Protein Synonyms/Alias
  
Gene Name
 SLC6A9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
503VQPLHPDKAQIPIVGubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 522 AA 
Protein Sequence
MMVVSTYIGI YYNVVICIAF YYFFSSMTHV LPWAYCNNPW NTHDCAGVLD ASNLTNGSRP 60
AALPSNLSHL LNHSLQRTSP SEEYWRLYVL KLSDDIGNFG EVRLPLLGCL GVSWLVVFLC 120
LIRGVKSSGK VVYFTATFPY VVLTILFVRG VTLEGAFDGI MYYLTPQWDK ILEAKVWGDA 180
ASQIFYSLGC AWGGLITMAS YNKFHNNCYR DSVIISITNC ATSVYAGFVI FSILGFMANH 240
LGVDVSRVAD HGPGLAFVAY PEALTLLPIS PLWSLLFFFM LILLGLGTQF CLLETLVTAI 300
VDEVGNEWIL QKKTYVTLGV AVAGFLLGIP LTSQAGIYWL LLMDNYAASF SLVVISCIMC 360
VAIMYIYGHR NYFQDIQMML GFPPPLFFQI CWRFVSPAII FFILVFTVIQ YQPITYNHYQ 420
YPGWAVAIGF LMALSSVLCI PLYAMFRLCR TDGDTLLQRL KNATKPSRDW GPALLEHRTG 480
RYAPTIAPSP EDGFEVQPLH PDKAQIPIVG SNGSSRLQDS RI 522 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IEA:InterPro.
 GO:0015187; F:glycine transmembrane transporter activity; IEA:Compara.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
 GO:0005283; F:sodium:amino acid symporter activity; IEA:InterPro. 
Interpro
 IPR000175; Na/ntran_symport.
 IPR003028; Na/ntran_symport_glycine_GLY1. 
Pfam
 PF00209; SNF 
SMART
  
PROSITE
 PS00754; NA_NEUROTRAN_SYMP_2
 PS50267; NA_NEUROTRAN_SYMP_3 
PRINTS
 PR01204; GLY1TRNSPORT.
 PR00176; NANEUSMPORT.