CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035786
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GCN5 general control of amino acid synthesis-like 2 (Yeast) (Predicted) 
Protein Synonyms/Alias
 Protein Kat2a 
Gene Name
 Kat2a 
Gene Synonyms/Alias
 Gcn5l2_predicted; rCG_33366 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
716TGWKPLGKEKGKELKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Bromodomain; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 832 AA 
Protein Sequence
MAEPSQAPNP APAAQPRPLQ SPAPAPTSTP APSPASAPTP APTPAPAPAP AAAPAGSTGT 60
GGAGVGSGGD PARPGLSQQQ RASQRKAQVR GLPRAKKLEK LGVFSACKAN ETCKCNGWKN 120
PKPPTAPRMD LQQPAANLSE LCRSCEHPLA DHVSHLENVS EDEINRLLGM VVDVENLFMS 180
VHKEEDTDTK QVYFYLFKLL RKCILQMTRP VVEGSLGSPP FEKPNIEQGV LNFVQYKFSH 240
LAPRERQTMF ELSKMFLLCL NYWKLETPAQ FRQRSQSEDV ATYKVNYTRW LCYCHVPQSC 300
DSLPRYETTH VFGRSLLRSI FTVTRRQLLE KFRVEKDKLV PEKRTLILTH FPKFLSMLEE 360
EIYGANSPIW ESGFTMPPSE GTQLVPRPAT VSATVVPSTP IFSPSMGGGS NSSLSLDSTG 420
TEPMPGEKRK LPENLTLEDA KRLRVMGDIP MELVNEVMLT ITDPAAMLGP ETSLLSANAA 480
RDETARLEER RGIIEFHVIG NSLTPKANRR VLLWLVGLQN VFSHQLPRMP KEYIARLVFD 540
PKHKTLALIK DGRVIGGICF RMFPTQGFTE IVFCAVTSNE QVKGYGTHLM NHLKEYHIKH 600
SILYFLTYAD EYAIGYFKKQ GFSKDIKVPK SRYLGYIKDY EGATLMECEL NPRIPYTELS 660
HIIKKQKEII KKLIERKQAQ IRKVYPGLSC FKEGVRQIPV ESVPGIRETG WKPLGKEKGK 720
ELKDPDQLYT TLKNLLAQIK SHPSAWPFME PVKKSEAPDY YEVIRFPIDL KTMTERLRSR 780
YYVTRKLFVA DLQRVIANCR EYNPPDSEYC RCASALEKFF YFKLKEGGLI DK 832 
Gene Ontology
 GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IEA:Compara.
 GO:0072686; C:mitotic spindle; IEA:Compara.
 GO:0030914; C:STAGA complex; IEA:Compara.
 GO:0033276; C:transcription factor TFTC complex; IEA:Compara.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0010484; F:H3 histone acetyltransferase activity; IEA:Compara.
 GO:0043997; F:histone acetyltransferase activity (H4-K12 specific); IEA:Compara.
 GO:0003713; F:transcription coactivator activity; IEA:Compara.
 GO:0008283; P:cell proliferation; IEA:Compara.
 GO:0016578; P:histone deubiquitination; IEA:Compara.
 GO:0044154; P:histone H3-K14 acetylation; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0022037; P:metencephalon development; IEA:Compara.
 GO:0030901; P:midbrain development; IEA:Compara.
 GO:0035264; P:multicellular organism growth; IEA:Compara.
 GO:0001843; P:neural tube closure; IEA:Compara.
 GO:0042981; P:regulation of apoptotic process; IEA:Compara.
 GO:0031647; P:regulation of protein stability; IEA:Compara.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
 GO:0001756; P:somitogenesis; IEA:Compara.
 GO:0021537; P:telencephalon development; IEA:Compara. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR001487; Bromodomain.
 IPR018359; Bromodomain_CS.
 IPR000182; GNAT_dom.
 IPR016376; Hist_acetylase_PCAF.
 IPR009464; PCAF_N. 
Pfam
 PF13508; Acetyltransf_7
 PF00439; Bromodomain
 PF06466; PCAF_N 
SMART
 SM00297; BROMO 
PROSITE
 PS00633; BROMODOMAIN_1
 PS50014; BROMODOMAIN_2
 PS51186; GNAT 
PRINTS
 PR00503; BROMODOMAIN.