UniProt Accession

 LYRM7_HUMAN; Q5U5X0; A8MPQ9; Q86Y68 

Genbank Protein ID

 AC004650; AC005179; CH471062; BC037930; BC047079 

Genbank Nucleotide ID

 EAW62375.1; AAH37930.1; AAH47079.1 

Protein Name

 Complex III assembly factor LYRM7 

Protein Synonyms/Alias

 LYR motif-containing protein 7 

Gene Name

 LYRM7 

Gene Synonyms/Alias

 C5orf31; MZM1L 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
6	**MGRAVKVLQLFKT	ubiquitination	[1, 2]
82	HTDHNTLKLVPRKDL	ubiquitination	[1, 2]
87	TLKLVPRKDLLVENV	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. 

Sequence Annotation

  

Keyword

 Chaperone; Complete proteome; Mitochondrion; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 104 AA 

Protein Sequence

Gene Ontology

 GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. 

Interpro

 IPR008011; Complex1_LYR. 

Pfam

 PF05347; Complex1_LYR 

SMART

  

PROSITE

  

PRINTS