CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029082
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 3'(2'),5'-bisphosphate nucleotidase 1 
Protein Synonyms/Alias
  
Gene Name
 BPNT1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
49CATDLQTKADRLAQMacetylation[1]
49CATDLQTKADRLAQMubiquitination[1, 2, 3, 4]
204LKEVPAGKHIITTTRubiquitination[1, 4]
260FASPGCKKWDTCAPEubiquitination[4]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 291 AA 
Protein Sequence
MASSNTVLMR LVASAYSIAQ KAGMIVRRVI AEGDLGIVEK TCATDLQTKA DRLAQMSICS 60
SLARKFPKLT IIGEEDLPSE EVDQELIEDS QWEEILKQPC PSQYSAIKEE DLVVWVDPLD 120
GTKEYTEGLL DNVTVLIGIA YEGKAIAGVI NQPYYNYENN EKQQLREHRN EAKAGPDAVL 180
GRTIWGVLGL GAFGFQLKEV PAGKHIITTT RSHSNKLVTD CVAAMNPDAV LRVGGAGNKI 240
IQLIEGKASA YVFASPGCKK WDTCAPEVIL HAVGGKLTDI HGNVLQYHKD V 291 
Gene Ontology
 GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. 
Interpro
 IPR020583; Inositol_monoP_metal-BS.
 IPR000760; Inositol_monophosphatase.
 IPR020550; Inositol_monophosphatase_CS. 
Pfam
 PF00459; Inositol_P 
SMART
  
PROSITE
 PS00629; IMP_1
 PS00630; IMP_2 
PRINTS