CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033294
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Fos-related antigen 2 
Protein Synonyms/Alias
  
Gene Name
 FOSL2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
65LPRPGVIKTIGTTVGacetylation[1, 2]
183SVGAVVVKQEPLEEDacetylation[2]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 202 AA 
Protein Sequence
MPGSGSAFIP TINAITTSQD LQWMVQPTVI TSMSNPYPRS HPYSPLPGLA SVPGHMALPR 60
PGVIKTIGTT VGRRRRDEQL SPEEEEKRRI RRERNKLAAA KCRNRRRELT EKLQAETEEL 120
EEEKSGLQKE IAELQKEKEK LEFMLVAHGP VCKISPEERR SPPAPGLQPM RSGGGSVGAV 180
VVKQEPLEED SPSSSSAGLD KA 202 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Compara. 
Interpro
 IPR004827; bZIP.
 IPR000837; Leuzip_Fos. 
Pfam
 PF00170; bZIP_1 
SMART
 SM00338; BRLZ 
PROSITE
 PS50217; BZIP
 PS00036; BZIP_BASIC 
PRINTS
 PR00042; LEUZIPPRFOS.