CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004160
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Mannosyl-D-glycerate transport/metabolism system repressor MngR 
Protein Synonyms/Alias
 Fatty acyl-responsive regulator; Protein P30 
Gene Name
 mngR 
Gene Synonyms/Alias
 farR; g30; ybgB; b0730; JW0719 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
87QLTSFDEKLSDRHVDacetylation[1]
199LLNISQTKPILEKVSacetylation[1]
204QTKPILEKVSRGYLVacetylation[1]
229AFNTDDYKFTLIAQRacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Represses mngA and mngB. Regulates its own expression. 
Sequence Annotation
 DOMAIN 4 72 HTH gntR-type.
 DNA_BIND 32 51 H-T-H motif (By similarity).  
Keyword
 Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 240 AA 
Protein Sequence
MGHKPLYRQI ADRIREQIAR GELKPGDALP TESALQTEFG VSRVTVRQAL RQLVEQQILE 60
SIQGSGTYVK EERVNYDIFQ LTSFDEKLSD RHVDTHSEVL IFEVIPADDF LQQQLQITPQ 120
DRVWHVKRVR YRKQKPMALE ETWMPLALFP DLTWQVMENS KYHFIEEVKK MVIDRSEQEI 180
IPLMPTEEMS RLLNISQTKP ILEKVSRGYL VDGRVFEYSR NAFNTDDYKF TLIAQRKSSR 240 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:EcoCyc.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR000524; Tscrpt_reg_HTH_GntR.
 IPR011663; UTRA.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00392; GntR
 PF07702; UTRA 
SMART
 SM00345; HTH_GNTR
 SM00866; UTRA 
PROSITE
 PS50949; HTH_GNTR 
PRINTS
 PR00035; HTHGNTR.