| Tag | Content |
|---|
| CPLM ID | CPLM-016346 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tyrosine-protein kinase SgK223 |
Protein Synonyms/Alias | Sugen kinase 223 |
Gene Name | SGK223 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1361 | KRALMMMKFAEKAVD | acetylation | [1] |
|
Reference | [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. Science. 2009 Aug 14;325(5942):834-40. [ PMID: 19608861] |
Functional Description | |
Sequence Annotation | DOMAIN 976 1325 Protein kinase.
NP_BIND 982 990 ATP (By similarity).
ACT_SITE 1143 1143 Proton acceptor (By similarity).
BINDING 1022 1022 ATP (By similarity).
MOD_RES 694 694 Phosphoserine.
MOD_RES 743 743 Phosphoserine.
MOD_RES 824 824 Phosphoserine. |
Keyword | ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Transferase; Tyrosine-protein kinase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1402 AA |
Protein Sequence | MHQTLCLNPE SLKMSACSDF VEHIWKPGSC KNCFCLRSDH QLVAGPPQPR AGSLPPPPRL 60
PPRPENCRLE DEGVNSSPYS KPTIAVKPTM MSSEASDVWT EANLSAEVSQ VIWRRAPGKL 120
PLPKQEDAPV VYLGSFRGVQ KPAGPSTSPD GNSRCPPAYT MVGLHNLEPR GERNIAFHPV 180
SFPEEKAVHK EKPSFPYQDR PSTQESFRQK LAAFAGTTSG CHQGPGPLRE SLPSEDDSDQ 240
RCSPSGDSEG GEYCSILDCC PGSPVAKAAS QTAGSRGRHG GRDCSPTCWE QGKCSGPAEQ 300
EKRGPSFPKE CCSQGPTAHP SCLGPKKLSL TSEAAISSDG LSCGSGSGSG ASSPFVPHLE 360
SDYCSLMKEP APEKQQDPGC PGVTPSRCLG LTGEPQPPAH PREATQPEPI YAESTKRKKA 420
APVPSKSQAK IEHAAAAQGQ GQVCTGNAWA QKAASGWGRD SPDPTPQVSA TITVMAAHPE 480
EDHRTIYLSS PDSAVGVQWP RGPVSQNSEV GEEETSAGQG LSSRESHAHS ASESKPKERP 540
AIPPKLSKSS PVGSPVSPSA GGPPVSPLAD LSDGSSGGSS IGPQPPSQGP ADPAPSCRTN 600
GVAISDPSRC PQPAASSASE QRRPRFQAGT WSRQCRIEEE EEVEQELLSH SWGRETKNGP 660
TDHSNSTTWH RLHPTDGSSG QNSKVGTGMS KSASFAFEFP KDRSGIETFS PPPPPPKSRH 720
LLKMNKSSSD LEKVSQGSAE SLSPSFRGVH VSFTTGSTDS LASDSRTCSD GGPSSELAHS 780
PTNSGKKLFA PVPFPSGSTE DVSPSGPQQP PPLPQKKIVS RAASSPDGFF WTQGSPKPGT 840
ASPKLNLSHS ETNVHDESHF SYSLSPGNRH HPVFSSSDPL EKAFKGSGHW LPAAGLAGNR 900
GGCGSPGLQC KGAPSASSSQ LSVSSQASTG STQLQLHGLL SNISSKEGTY AKLGGLYTQS 960
LARLVAKCED LFMGGQKKEL HFNENNWSLF KLTCNKPCCD SGDAIYYCAT CSEDPGSTYA 1020
VKICKAPEPK TVSYCSPSVP VHFNIQQDCG HFVASVPSSM LSSPDAPKDP VPALPTHPPA 1080
QEQDCVVVIT REVPHQTASD FVRDSAASHQ AEPEAYERRV CFLLLQLCNG LEHLKEHGII 1140
HRDLCLENLL LVHCTLQAGP GPAPAPAPAP AAAAPPCSSA APPAGGTLSP AAGPASPEGP 1200
REKQLPRLII SNFLKAKQKP GGTPNLQQKK SQARLAPEIV SASQYRKFDE FQTGILIYEL 1260
LHQPNPFEVR AQLRERDYRQ EDLPPLPALS LYSPGLQQLA HLLLEADPIK RIRIGEAKRV 1320
LQCLLWGPRR ELVQQPGTSE EALCGTLHNW IDMKRALMMM KFAEKAVDRR RGVELEDWLC 1380
CQYLASAEPG ALLQSLKLLQ LL 1402 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |