CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030533
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ34980 fis, clone OCBBF2000522, highly similar to Rab GTPase-binding effector protein 2 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
105EAQITALKQERQQQQubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 569 AA 
Protein Sequence
MAAAAPVAAD DDERRRRPGA ALEDSRSQEG ANGEAESGEL SRLRAELAGA LAEMETMKAV 60
AEVSESTKAE AVAAVQRQCQ EEVASLQAIL KDSISSYEAQ ITALKQERQQ QQQDCEEKER 120
ELGRLKQLLS RAYPLDSLEK QMEKAHEDSE KLREIVLPME KEIEELKAKL LRAEELIQEI 180
QRRPRHAPSL HGSTELLPLS RDPSPPLEPL EELSGDGGPA AEAFAHNCDD SASISSFSLG 240
GGVGSSSSLP QSRQGLSPEQ EETASLVSTG TLVPEGIYLP PPGYQLVPDT QWEQLQTEGR 300
QLQKDLESVS RERDELQEGL RRSNEDCAKQ MQVLLAQVQN SEQLLRTLQG TVSQAQERVQ 360
LQMAELVTTH KCLHHEVKRL NEENQGLRAE QPPSSAPQGS QQEQGEEESL PSSVPELQQL 420
LCCTRQEARA RLQAQEHGAE RLRIEIVTLR EALEEETVAR ASLEGQLRVQ REETEVLEAS 480
LCSLRTEMER VQQEQSKAQL PDLLSEQRAK VLRLQAELET SEQVQRDFVR LSQALQVRLE 540
RIRQAETLEQ VRSIMDEAPL TDVRDIKDT 569 
Gene Ontology
 GO:0005096; F:GTPase activator activity; IEA:InterPro.
 GO:0043547; P:positive regulation of GTPase activity; IEA:GOC. 
Interpro
 IPR003914; Rabaptin.
 IPR018514; Rabaptin_coiled-coil.
 IPR015390; Rabaptin_Rab5-bd_dom. 
Pfam
 PF09311; Rab5-bind
 PF03528; Rabaptin 
SMART
  
PROSITE
  
PRINTS
 PR01432; RABAPTIN.