Tag | Content |
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CPLM ID | CPLM-017139 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable G-protein coupled receptor 115 |
Protein Synonyms/Alias | G-protein coupled receptor PGR18 |
Gene Name | GPR115 |
Gene Synonyms/Alias | PGR18 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
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42 | KLQSPEGKPKTGRIQ | ubiquitination | [1] |
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Reference | [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA. Mol Cell Proteomics. 2012 May;11(5):148-59. [ PMID: 22505724] |
Functional Description | Orphan receptor. |
Sequence Annotation | DOMAIN 346 396 GPS. CARBOHYD 61 61 N-linked (GlcNAc...) (Potential). CARBOHYD 169 169 N-linked (GlcNAc...) (Potential). CARBOHYD 177 177 N-linked (GlcNAc...) (Potential). CARBOHYD 209 209 N-linked (GlcNAc...) (Potential). CARBOHYD 229 229 N-linked (GlcNAc...) (Potential). CARBOHYD 250 250 N-linked (GlcNAc...) (Potential). CARBOHYD 257 257 N-linked (GlcNAc...) (Potential). CARBOHYD 263 263 N-linked (GlcNAc...) (Potential). CARBOHYD 264 264 N-linked (GlcNAc...) (Potential). CARBOHYD 286 286 N-linked (GlcNAc...) (Potential). CARBOHYD 309 309 N-linked (GlcNAc...) (Potential). CARBOHYD 340 340 N-linked (GlcNAc...) (Potential). CARBOHYD 379 379 N-linked (GlcNAc...) (Potential). |
Keyword | Cell membrane; Complete proteome; G-protein coupled receptor; Glycoprotein; Membrane; Polymorphism; Receptor; Reference proteome; Signal; Transducer; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 695 AA |
Protein Sequence | MKMKSQATMI CCLVFFLSTE CSHYRSKIHL KAGDKLQSPE GKPKTGRIQE KCEGPCISSS 60 NCSQPCAKDF HGEIGFTCNQ KKWQKSAETC TSLSVEKLFK DSTGASRLSV AAPSIPLHIL 120 DFRAPETIES VAQGIRKNCP FDYACITDMV KSSETTSGNI AFIVELLKNI STDLSDNVTR 180 EKMKSYSEVA NHILDTAAIS NWAFIPNKNA SSDLLQSVNL FARQLHIHNN SENIVNELFI 240 QTKGFHINHN TSEKSLNFSM SMNNTTEDIL GMVQIPRQEL RKLWPNASQA ISIAFPTLGA 300 ILREAHLQNV SLPRQVNGLV LSVVLPERLQ EIILTFEKIN KTRNARAQCV GWHSKKRRWD 360 EKACQMMLDI RNEVKCRCNY TSVVMSFSIL MSSKSMTDKV LDYITCIGLS VSILSLVLCL 420 IIEATVWSRV VVTEISYMRH VCIVNIAVSL LTANVWFIIG SHFNIKAQDY NMCVAVTFFS 480 HFFYLSLFFW MLFKALLIIY GILVIFRRMM KSRMMVIGFA IGYGCPLIIA VTTVAITEPE 540 KGYMRPEACW LNWDNTKALL AFAIPAFVIV AVNLIVVLVV AVNTQRPSIG SSKSQDVVII 600 MRISKNVAIL TPLLGLTWGF GIATLIEGTS LTFHIIFALL NAFQGFFILL FGTIMDHKIR 660 DALRMRMSSL KGKSRAAENA SLGPTNGSKL MNRQG 695 |
Gene Ontology | GO:0016021; C:integral to membrane; TAS:GDB. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0004930; F:G-protein coupled receptor activity; TAS:GDB. GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |