UniProt Accession

 MAP4_RAT; Q5M7W5; Q75NR5; Q75NR6 

Genbank Protein ID

 BC088405; AB175782; AB175783 

Genbank Nucleotide ID

 AAH88405.1; BAD14292.1; BAD14293.1 

Protein Name

 Microtubule-associated protein 4 

Protein Synonyms/Alias

 MAP-4 

Gene Name

 Map4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
233	AVDLESVKEQLPAKA	acetylation	[1]
347	EEETVPGKDMTFPKE	acetylation	[1]
622	DEGSPLEKLEQKETS	acetylation	[1]
647	VSRQEEGKAAVGLTG	acetylation	[1]
671	ELPPSPEKKAKPLAT	acetylation	[1]
748	PARDLKPKPITETKV	acetylation	[1]
816	TTTKTEGKPADVKRM	acetylation	[1]
821	EGKPADVKRMTAKSA	acetylation	[1]
907	TVSAPDLKSVRSKVG	acetylation	[1]
933	GRVQIQNKKVDISKV	acetylation	[1]
939	NKKVDISKVSSKCGS	acetylation	[1]
960	KPGGGDVKIESQKLN	acetylation	[1]
969	ESQKLNFKEKAQAKV	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Non-neuronal microtubule-associated protein. Promotes microtubule assembly (By similarity). 

Sequence Annotation

 REPEAT 897 927 Tau/MAP 1.
 REPEAT 928 958 Tau/MAP 2.
 REPEAT 959 990 Tau/MAP 3.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 60 60 Phosphoserine (By similarity).
 MOD_RES 99 99 Phosphoserine (By similarity).
 MOD_RES 260 260 Phosphoserine (By similarity).
 MOD_RES 497 497 Phosphothreonine (By similarity).
 MOD_RES 506 506 Phosphothreonine (By similarity).
 MOD_RES 509 509 Phosphoserine (By similarity).
 MOD_RES 520 520 Phosphoserine (By similarity).
 MOD_RES 522 522 Phosphoserine (By similarity).
 MOD_RES 546 546 Phosphothreonine (By similarity).
 MOD_RES 599 599 Phosphoserine (By similarity).
 MOD_RES 618 618 Phosphoserine (By similarity).
 MOD_RES 631 631 Phosphoserine (By similarity).
 MOD_RES 668 668 Phosphoserine (By similarity).
 MOD_RES 761 761 Phosphoserine (By similarity).
 MOD_RES 785 785 Phosphothreonine (By similarity).
 MOD_RES 786 786 Phosphoserine (By similarity).
 MOD_RES 799 799 Phosphoserine (By similarity).
 MOD_RES 801 801 Phosphoserine (By similarity).
 MOD_RES 848 848 Phosphothreonine (By similarity).
 MOD_RES 902 902 Phosphoserine (By similarity).
 MOD_RES 915 915 Phosphoserine; by MARK1 (Probable).
 MOD_RES 916 916 Phosphothreonine (By similarity).
 MOD_RES 978 978 Phosphoserine (By similarity).
 MOD_RES 1050 1050 Phosphoserine (By similarity).
 MOD_RES 1056 1056 Phosphoserine (By similarity).  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 1057 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW. 

Interpro

 IPR027324; MAP2/MAP4/Tau.
 IPR027323; MAP4.
 IPR001084; Tau/MAP_tubulin-bd_rpt. 

Pfam

 PF00418; Tubulin-binding 

SMART

  

PROSITE

 PS00229; TAU_MAP_1
 PS51491; TAU_MAP_2 

PRINTS