UniProt Accession

 AB17B_HUMAN; Q5VST6; A8KAJ5; Q5VST7; Q86YB6; Q8IY03; Q9Y377 

Genbank Protein ID

 AF151825; AK293060; AL138751; AL671309; AL138751; AL671309; AL671309; AL138751; AL671309; AL138751; CH471089; BC038390; BC044576 

Genbank Nucleotide ID

 AAD34062.1; BAF85749.1; CAH72763.1; CAH72763.1; CAH72764.1; CAH72764.1; CAH73542.1; CAH73542.1; CAH73543.1; CAH73543.1; EAW62521.1; AAH38390.2; AAH44576.1 

Protein Name

 Alpha/beta hydrolase domain-containing protein 17B 

Protein Synonyms/Alias

  

Gene Name

 ABHD17B 

Gene Synonyms/Alias

 C9orf77; FAM108B1; CGI-67 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
63	WQYSSREKDAIECFM	ubiquitination	[1, 2]
136	GYGASSGKPTEKNLY	ubiquitination	[1, 2, 3]
206	RVAFPDTKKTYCFDA	ubiquitination	[1, 3, 4]
207	VAFPDTKKTYCFDAF	ubiquitination	[1, 2]
278	GQYLERLKQFVSQEL	ubiquitination	[1, 2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 ACT_SITE 170 170 Charge relay system (By similarity).
 ACT_SITE 235 235 Charge relay system (By similarity).
 ACT_SITE 264 264 Charge relay system (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Hydrolase; Polymorphism; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 288 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS