| Tag | Content |
|---|
| CPLM ID | CPLM-005640 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dynactin subunit 1 |
Protein Synonyms/Alias | 150 kDa dynein-associated polypeptide; DAP-150; DP-150; p150-glued |
Gene Name | Dctn1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1153 | LSGALYRKTSQLLEK | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein- dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. |
Sequence Annotation | DOMAIN 48 90 CAP-Gly.
MOD_RES 108 108 Phosphothreonine (By similarity).
MOD_RES 540 540 Phosphoserine (By similarity). |
Keyword | 3D-structure; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Dynein; Microtubule; Phosphoprotein; Reference proteome; Transport; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1280 AA |
Protein Sequence | MAQSKRHMYN RTPSGSRMST EASARPLRVG SRVEVIGKGH RGTVAYVGAT LFATGKWVGV 60
ILDEAKGKND GTVQGRKYFT CDEGHGIFVR QSQIQVFEDG ADTTSPETPD SSASKILKRE 120
GADAAAKTSK LRGLKPKKAP TARKTTTRRP KPTRPASTGV AGPSSSLGPS GSASAGELSS 180
SEPSTPAQTP LAAPIIPTPA LTSPGAAPPL PSPSKEEEGL RDQVRDLEEK LETLRLKRSE 240
DKAKLKELEK HKIQLEQVQE WKSKMQEQQA DLQRRLKEAK EAKEALEAKE RYMEEMADTA 300
DAIEMATLDK EMAEERAESL QQEVEALKER VDELTTDLEI LKAEIEEKGS DGAASSYQLK 360
QLEEQNARLK DALVRMRDLS SSEKQEHVKL QKLMEKKNQE LEVVRQQRER LQEELSQAES 420
TIDELKEQVD AALGAEEMVE MLTDRNLNLE EKVRELRETV GDLEAMNEMN DELQENARET 480
ELELREQLDM AGARVREAQK RVEAAQETVA DYQQTIKKYR QLTAHLQDVN RELTNQQEAS 540
VERQQQPPPE TFDFKIKFAE TKAHAKAIEM ELRQMEVAQA NRHMSLLTAF MPDSFLRPGG 600
DHDCVLVLLL MPRLICKAEL IRKQAQEKFD LSENCSERPG LRGAAGEQLS FAAGLVYSLS 660
LLQATLHRYE HALSQCSVDV YKKVGSLYPE MSAHERSLDF LIELLHKDQL DETVNVEPLT 720
KAIKYYQHLY SIHLAEQPEE STMQLADHIK FTQSALDCMS VEVGRLRAFL QGGQEATDIA 780
LLLRDLETSC SDIRQFCKKI RRRMPGTDAP GIPAALAFGS QVSDTLLDCR KHLTWVVAVL 840
QEVAAAAAQL IAPLAENEGL PVAALEELAF KASEQIYGSP SSSPYECLRQ SCSILISTMN 900
KLATAMQEGE YDAERPPSKP PPVEPWPAAL RAEITDAEGL GLKLEDRETV IKELKKSLKI 960
KGEELSEANV RLSLLEKKLD SAAKDADERI EKVQTRLEET QTLLRKKEKE FEETMDALQA 1020
DIDQLEAEKT ELKQRLNSQS KRTIEGLRGP PPSGIATLVS GIAGEEQQRG GTPGQAPGAL 1080
PGPGPVKDSP LLLQQISAMR LHISQLQHEN SILRGAQMKA SLAALPPLHV AKFSLPPHEG 1140
PGGNLLSGAL YRKTSQLLEK LNQLSTYTHV VDITRSSPAC KSPSAQLMEQ VAQLKSLSDT 1200
IEKLKDEVLK ETVTQRPGAT VPTDFATFPS SAFLRAKEEQ QDDTVYMGKV TFSCAAGLGQ 1260
RHRLVLTQEQ LHQLHGRLIS 1280 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |