CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008291
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serpin B9 
Protein Synonyms/Alias
 Cytoplasmic antiproteinase 3; CAP-3; CAP3; Peptidase inhibitor 9; PI-9 
Gene Name
 SERPINB9 
Gene Synonyms/Alias
 PI9 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
297VDAFQQGKADLSAMSubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Granzyme B inhibitor. 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Protease inhibitor; Reference proteome; Serine protease inhibitor. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 376 AA 
Protein Sequence
METLSNASGT FAIRLLKILC QDNPSHNVFC SPVSISSALA MVLLGAKGNT ATQMAQALSL 60
NTEEDIHRAF QSLLTEVNKA GTQYLLRTAN RLFGEKTCQF LSTFKESCLQ FYHAELKELS 120
FIRAAEESRK HINTWVSKKT EGKIEELLPG SSIDAETRLV LVNAIYFKGK WNEPFDETYT 180
REMPFKINQE EQRPVQMMYQ EATFKLAHVG EVRAQLLELP YARKELSLLV LLPDDGVELS 240
TVEKSLTFEK LTAWTKPDCM KSTEVEVLLP KFKLQEDYDM ESVLRHLGIV DAFQQGKADL 300
SAMSAERDLC LSKFVHKSFV EVNEEGTEAA AASSCFVVAE CCMESGPRFC ADHPFLFFIR 360
HNRANSILFC GRFSSP 376 
Gene Ontology
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0005615; C:extracellular space; IDA:UniProtKB.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
 GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
 GO:0071391; P:cellular response to estrogen stimulus; IEP:UniProtKB.
 GO:0006955; P:immune response; IDA:UniProtKB.
 GO:0002448; P:mast cell mediated immunity; IEP:UniProtKB.
 GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
 GO:0030162; P:regulation of proteolysis; IBA:RefGenome. 
Interpro
 IPR023795; Protease_inhib_I4_serpin_CS.
 IPR000240; Serpin_B9/Maspin.
 IPR023796; Serpin_dom.
 IPR000215; Serpin_fam. 
Pfam
 PF00079; Serpin 
SMART
 SM00093; SERPIN 
PROSITE
 PS00284; SERPIN 
PRINTS
 PR00676; MASPIN.