CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007970
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L6 
Protein Synonyms/Alias
 TAX-responsive enhancer element-binding protein 107; TAXREB107 
Gene Name
 Rpl6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
13APDTKEKKPAAKKAGacetylation[1]
95EKKKKKEKVLATVTKacetylation[1]
95EKKKKKEKVLATVTKubiquitination[2]
102KVLATVTKTVGGDKNubiquitination[2]
108TKTVGGDKNGGTRVVacetylation[1]
208FVIATSTKVDISDVKubiquitination[2]
215KVDISDVKIPKHLTDubiquitination[2]
218ISDVKIPKHLTDAYFubiquitination[2]
226HLTDAYFKKKQLRKPubiquitination[2]
245GEIFDTEKEKYEITEacetylation[1]
245GEIFDTEKEKYEITEubiquitination[2]
247IFDTEKEKYEITEQRacetylation[1]
259EQRKADQKAVDLQILubiquitination[2]
270LQILPKIKAVPQLQGubiquitination[2]
293TNGMYPHKLVF****ubiquitination[2]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 MOD_RES 135 135 Phosphoserine (By similarity).
 MOD_RES 226 226 N6-acetyllysine (By similarity).
 MOD_RES 247 247 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 296 AA 
Protein Sequence
MAGEKAPDTK EKKPAAKKAG SDAAASRPRA AKVAKKVHPK GKKPKKAKPH CSRNPVLVRG 60
IGRYSRSAMY SRKALYKRKY SAAKTKVEKK KKKEKVLATV TKTVGGDKNG GTRVVKLRKM 120
PRYYPTEDVP RKLLSHGKKP FSQHVRRLRS SITPGTVLII LTGRHRGKRV VFLKQLDSGL 180
LLVTGPLVIN RVPLRRTHQK FVIATSTKVD ISDVKIPKHL TDAYFKKKQL RKPRHQEGEI 240
FDTEKEKYEI TEQRKADQKA VDLQILPKIK AVPQLQGYLR SQFSLTNGMY PHKLVF 296 
Gene Ontology
 GO:0005737; C:cytoplasm; ISA:MGI.
 GO:0005730; C:nucleolus; ISA:MGI.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR014722; Rib_L2_dom2.
 IPR005568; Ribosomal_L6_N.
 IPR000915; Ribosomal_L6E. 
Pfam
 PF01159; Ribosomal_L6e
 PF03868; Ribosomal_L6e_N 
SMART
  
PROSITE
 PS01170; RIBOSOMAL_L6E 
PRINTS