CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023442
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nitric oxide synthase-interacting protein homolog 
Protein Synonyms/Alias
  
Gene Name
 CG6179 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
106LSQEANSKQQARMERacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 307 AA 
Protein Sequence
MTRHARNCTA GAVYTYNEKK RDAAESGYGT NAQRLGKDSV KSFDCCSLTL QPCRRPVITK 60
DGYLFDKEAI LQYIVTKKNE YSRRLKEYER LRRAEEDKLS QEANSKQQAR MERFVNAEKP 120
AMTPAHSSAA ASEKPSTSSA AAAASSESSS ASSISNMTNG HEKKLPSFWL PSECPNAGLA 180
KAQKPDATIY CPVSQKPLRV KDLIDVKFTL LKDGDTKRSL IAKEARYMCP ITHDVLSNAV 240
PCAVLRPTGD VVTMECVERL IRKDMIHPLT DRKLKEKDII PLQRGGTGYA TTNDHLQAKE 300
KRPMLQA 307 
Gene Ontology
 GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0000398; P:mRNA splicing, via spliceosome; IC:FlyBase.
 GO:0051001; P:negative regulation of nitric-oxide synthase activity; ISS:UniProtKB. 
Interpro
 IPR016818; Nitric_oxide_synth-interacting.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
  
PROSITE
  
PRINTS