| Tag | Content |
|---|
| CPLM ID | CPLM-007366 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | U3 small nucleolar RNA-associated protein 25 |
Protein Synonyms/Alias | U3 snoRNA-associated protein 25; U three protein 25 |
Gene Name | UTP25 |
Gene Synonyms/Alias | YIL091C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 396 | KFTRKAIKLYSNFYQ | ubiquitination | [1] | | 692 | TVRCIYSKLDGLSLE | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. |
Sequence Annotation | MOD_RES 53 53 Phosphoserine.
MOD_RES 63 63 Phosphoserine.
MOD_RES 196 196 Phosphoserine. |
Keyword | Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; rRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 721 AA |
Protein Sequence | MSDSSVREKN DNFRGYRKRG RQELRKIKRS SARTEGGSTE TLEDVAEDID HRSDEDEVSD 60
VDSGDDFDIE DEEGKKEKVY DALLTILKSE HPEPKRRRRE ADESNKAPAE VGEDEHENTE 120
HGPVDDQLEI ENGLLGNHED DNDDDSSGDE KDIDSEDEQD PFESHFNQVP EKFVDKLSNA 180
FKTKSVKYKS VKGSLSDSES YIYAKPVVIG EEALVESPYR SSSIYSYFLK QRLKVQNGLL 240
DKKTDPLTAL QKKLVDPMFQ YKDILYEYDS YEKDEDEYRD LYALHVLNHI YKTRDRILKN 300
NQRLQDNPDT EHLDQGFTRP KVLIVVPTRE VAYRVVDKII SKSGIDQVDK KGKFYDQFRD 360
DSLPPKSKPK SFQHIFRGNT NDFFVVGLKF TRKAIKLYSN FYQSDIIVCS PLGIQMILEN 420
TDKKKRQDDF LSSIELMVID QLHSIEYQNI SHIFTIFDHL NKIPDQQHEA DFSRIRMWYI 480
NEQAKLFRQT MVFTKYISPA ANSLINGRCR NMAGRWKNHK VIGSENSSIG QSGLKIRQIF 540
QRFDIIGNSI IEEPDYRFKF FTSVIIPGIV KSTGYEDGIL IYIPDYTDFI RIRNYMKEKT 600
TILFGDINEY SSQRQLNANR SLFQQGRLKV MLYTERLHHY RRYEIKGVKS VVFYKPPNNP 660
EFYNEVVRFI GKNAFLGNTD LNISTVRCIY SKLDGLSLER IVGTKRAAVL SHAQKEIYEF 720
K 721 |
Gene Ontology | GO:0005730; C:nucleolus; IDA:SGD. GO:0032040; C:small-subunit processome; IDA:SGD. GO:0019843; F:rRNA binding; IDA:SGD. GO:0034511; F:U3 snoRNA binding; IDA:SGD. GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |