CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028674
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Alpha-tocopherol transfer protein 
Protein Synonyms/Alias
  
Gene Name
 Ttpa 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
71DLAWRLMKNYYKWRAubiquitination[1]
125RIAYWDPKVFTAYDVubiquitination[1]
178ITPSVAKKIAAVLTDacetylation[2]
178ITPSVAKKIAAVLTDubiquitination[1]
190LTDSFPLKVRGIHLIubiquitination[1]
217IKPFLTEKIKDRFICubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice.
 Simon GM, Cheng J, Gordon JI.
 Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11133-8. [PMID: 22733758
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 262 AA 
Protein Sequence
MAEMRPGPLV GKQLNELPDH SPLLQPGLAE LRRRVQEAGV PQTPQPLTDA FLLRFLRARD 60
FDLDLAWRLM KNYYKWRAEC PELSADLRPR SILGLLKAGY HGVLRSRDST GSRVLIYRIA 120
YWDPKVFTAY DVFRVSLITS ELIVQEVETQ RNGVKAIFDL EGWQVSHAFQ ITPSVAKKIA 180
AVLTDSFPLK VRGIHLINEP VIFHAVFSMI KPFLTEKIKD RFICTGTTTN QACFSTSQTF 240
FLGNMAVKSS PWRIFVRSGQ IL 262 
Gene Ontology
 GO:0005737; C:cytoplasm; TAS:MGI.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0008431; F:vitamin E binding; TAS:MGI.
 GO:0001892; P:embryonic placenta development; IMP:MGI.
 GO:0042360; P:vitamin E metabolic process; IMP:MGI. 
Interpro
 IPR001071; CRAL-bd_toc_tran.
 IPR001251; CRAL-TRIO_dom.
 IPR011074; CRAL/TRIO_N_dom. 
Pfam
 PF00650; CRAL_TRIO
 PF03765; CRAL_TRIO_N 
SMART
 SM01100; CRAL_TRIO_N
 SM00516; SEC14 
PROSITE
 PS50191; CRAL_TRIO 
PRINTS
 PR00180; CRETINALDHBP.