UniProt Accession

 YHBJ_ECOLI; P0A894; P33995; Q2M907 

Genbank Protein ID

 Z27094; U12684; U18997; U00096; AP009048 

Genbank Nucleotide ID

 CAA81620.1; AAB60166.1; AAA58007.1; AAC76237.1; BAE77249.1 

Protein Name

 UPF0042 nucleotide-binding protein YhbJ 

Protein Synonyms/Alias

  

Gene Name

 yhbJ 

Gene Synonyms/Alias

 b3205; JW3172 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
108	RLHPLSSKNLSLESA	acetylation	[1]
118	SLESAIDKESDLLEP	acetylation	[1]
194	PNPHWDPKLRPMTGL	acetylation	[1]
203	RPMTGLDKPVAAFLD	acetylation	[1]
251	AIGCTGGKHRSVYIA	acetylation	[1, 2]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli.
 Zhang J, Sprung R, Pei J, Tan X, Kim S, Zhu H, Liu CF, Grishin NV, Zhao Y.
 Mol Cell Proteomics. 2009 Feb;8(2):215-25. [PMID: 18723842] 

Functional Description

 Displays ATPase and GTPase activities. Can also hydrolyze pNPP. May regulate expression of glmS, by affecting the processing and stability of a small RNA, glmZ. 

Sequence Annotation

 NP_BIND 8 15 ATP (Potential).
 NP_BIND 56 59 GTP (Potential).
 MOD_RES 251 251 N6-acetyllysine.  

Keyword

 Acetylation; ATP-binding; Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 284 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0005525; F:GTP binding; IEA:HAMAP.
 GO:0048518; P:positive regulation of biological process; IMP:EcoCyc.
 GO:0006396; P:RNA processing; IMP:EcoCyc. 

Interpro

 IPR005337; ATPase_P-loop-containing.
 IPR027417; P-loop_NTPase. 

Pfam

 PF03668; ATP_bind_2 

SMART

  

PROSITE

  

PRINTS