CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transposon Ty1-LR4 Gag polyprotein 
Protein Synonyms/Alias
 Gag-p49; Transposon Ty1 protein A; TY1A; TYA; p58; Capsid protein; CA; Gag-p45; p54; Gag-p4 
Gene Name
 TY1A-LR4 
Gene Synonyms/Alias
 YLRWTy1-4 GAG; YLR256W-A; L9672.1 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
430EPIQLNNKHDLHLRPacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome. The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules. CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity). 
Sequence Annotation
 REGION 299 401 RNA-binding (By similarity).
 MOD_RES 416 416 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Ribosomal frameshifting; RNA-binding; Transposable element. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 440 AA 
Protein Sequence
MESQQLSQHP HISHGSACAS VTSKEVHTNQ DPLDVSASKT EECEKASTKA NSQQTTTPAS 60
SAVPENPHHA SPQPASVPPP QNGPYPQQCM MTQNQANPSG WSFYGHPSMI PYTPYQMSPM 120
YFPPGPQSQF PQYPSSVGTP LSTPSPESGN TFTDSSSADS DMTSTKKYVR PPPMLTSPND 180
FPNWVKTYIK FLQNSNLGGI IPTVNGKPVR QITDDELTFL YNTFQIFAPS QFLPTWVKDI 240
LSVDYTDIMK ILSKSIEKMQ SDTQEANDIV TLANLQYNGS TPADAFETKV TNIIDRLNNN 300
GIHINNKVAC QLIMRGLSGE YKFLRYTRHR HLNMTVAELF LDIHAIYEEQ QGSRNSKPNY 360
RRNLSDEKND SRSYTNTTKP KVIARNPQKT NNSKSKTARA HNVSTSNNSP STDNDSISKS 420
TTEPIQLNNK HDLHLRPGTY 440 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0000943; C:retrotransposon nucleocapsid; ISS:SGD.
 GO:0003723; F:RNA binding; ISS:SGD.
 GO:0032197; P:transposition, RNA-mediated; ISS:SGD. 
Interpro
 IPR015820; Retrotransposon_Ty1A_N. 
Pfam
 PF01021; TYA 
SMART
  
PROSITE
  
PRINTS