CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038359
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Acyl-coenzyme A oxidase 
Protein Synonyms/Alias
  
Gene Name
 Acox3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
293MVGDIGKKLGQNGLDubiquitination[1]
334GTYNSPFKDVRQRLGubiquitination[1]
451HALASAGKPLASWTAubiquitination[1]
542YPGILGQKFLGSSKAubiquitination[1]
548QKFLGSSKADWMDSAacetylation[2]
548QKFLGSSKADWMDSAsuccinylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; FAD; Flavoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 728 AA 
Protein Sequence
MKLSFTSGTS QVPDLSPRNV ADTAPCAELS LLLRNGDKAG DSTMGSLPEE KDSALWSDTP 60
KGPLSAYRAR ASFNSGELLL FWDGQDVIHF KKTIFSTLEN DPLFARSYGA DLPLEKLREL 120
NFLRCKRVFE YGFFKVEELL KNPLKILVLI NCLGMYDWSL ANKCVLHMLV FGTTVFVSGS 180
EKHFKYLEKI YSLEIFGCFA LTELSHGSNT KAMRTTAHYD PDTQEFILHS PDFEAAKFWV 240
GNLGKTATHA VVFAQLYMPD GQCHGLHSFL VQIRDTKTLL PMTGVMVGDI GKKLGQNGLD 300
NGFAMFNKVR IPRQNLLDRT GNITSEGTYN SPFKDVRQRL GASLGSLSSG RISIISMSVV 360
NLKLAVSIAI RFSATRCQFG PTDKEEIPVL EYPLQQWRIL PYLAAAYALD HFSKTIFMDL 420
IEVQSARLRG DHSDQQAELG REIHALASAG KPLASWTAQR GIQECREACG GHGYLAMNRF 480
GDLRNDNDPN CTYEGDNNVL LQQTSNYLLS LLEPPLQDGA HFTSPLKTVD FLEAYPGILG 540
QKFLGSSKAD WMDSAAPLAA YRWLVCYLLQ ESHRRYCQEK KSRGSDFEAR NNSQVYGCRP 600
LALAFMELTV MQRFHEHIHS SGLSPSLRTV LGRLSTLYGL WCLSQHMALL YRGGYISGEQ 660
TGRAMEDAIL TLCEQLKDDA VALVDVIAPS DFVLNSPIAK ADGEVSDLAR YDLDLPPAWH 720
PFRLPLRN 728 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005782; C:peroxisomal matrix; TAS:MGI.
 GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0016402; F:pristanoyl-CoA oxidase activity; TAS:MGI.
 GO:0006635; P:fatty acid beta-oxidation; TAS:MGI. 
Interpro
 IPR006090; Acyl-CoA_Oxase/DH_1.
 IPR006091; Acyl-CoA_Oxase/DH_cen-dom.
 IPR012258; Acyl-CoA_oxidase.
 IPR002655; Acyl-CoA_oxidase_C.
 IPR009075; AcylCo_DH/oxidase_C.
 IPR009100; AcylCoA_DH/oxidase. 
Pfam
 PF01756; ACOX
 PF00441; Acyl-CoA_dh_1
 PF02770; Acyl-CoA_dh_M 
SMART
  
PROSITE
  
PRINTS